Results 231 to 240 of about 2,570,442 (291)

Psilocybin in alcohol use disorder and comorbid depressive symptoms: Results from a feasibility randomized clinical trial

open access: yesAddiction, EarlyView.
Abstract Background and Aims Psilocybin has emerged as a potential treatment for alcohol use disorder (AUD), but early efficacy data are inconsistent. Depression following alcohol detoxification significantly increases the risk of relapse. This pilot study aimed to evaluate the feasibility, acceptability, and preliminary efficacy of psilocybin‐assisted
Amandine Luquiens   +7 more
wiley   +1 more source

Psilocybin‐assisted psychotherapy for methamphetamine use disorder: A pilot open‐label safety and feasibility study

open access: yesAddiction, EarlyView.
Abstract Background & Aims There are few effective treatments for methamphetamine use disorder, despite increasing global demand. Here, we assessed the safety and feasibility of outpatient psilocybin‐assisted psychotherapy for methamphetamine use disorder. Design Single arm, open label pilot study.
Elizabeth Knock   +8 more
wiley   +1 more source

5‐Methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) for alcohol use disorder: An open‐label, phase 2, proof‐of‐concept, clinical trial

open access: yesAddiction, EarlyView.
Abstract Background and Aims Psychedelic drugs may help treat alcohol use disorder (AUD). This study evaluated BPL‐003, a novel intranasal powder formulation of 5‐methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) benzoate salt, in people with moderate–severe AUD enrolled in a standard of care, 10‐week programme of relapse‐prevention oriented Cognitive ...
John Marsden   +10 more
wiley   +1 more source

The psychoactive effects of repeated ketamine infusions and their mechanistic role in the treatment of alcohol use disorder: Secondary analysis of a randomised controlled trial

open access: yesAddiction, EarlyView.
Abstract Background and aims Ketamine assisted psychotherapy is a promising new treatment for alcohol use disorder (AUD). The psychoactive effects of repeated intravenous (IV) ketamine infusions in people with AUD and their mechanistic role in treating AUD are largely unknown.
Cassie Bloy   +11 more
wiley   +1 more source

Transhumanism Without Transindividuation in the Age Without Epochality: Stiegler, Vice, and Radical Human Enhancement

open access: yesBioethics, EarlyView.
ABSTRACT At its core, transhumanism is utopic and apocalyptic: it tells us we will be saved through an imminent radical change of our being wrought by radical human enhancement (RHE) technologies. We are rushing, its supporters claim, towards a technological utopia so long as assorted techno‐phobes do not stand in the way.
Benjamin N. Parks
wiley   +1 more source

Associations between maths ability mindset, maths task preference and physiological responses to feedback during an arithmetic task across two primary school years

open access: yesBritish Journal of Educational Psychology, EarlyView.
Abstract Background Students' mindsets, reactions to feedback and learning‐related behaviour are important for academic success, yet little is known about how these factors and their interconnections develop during primary school. Aims To explore longitudinal associations between students' mindsets, physiological responses to performance feedback, and ...
Ita Puusepp   +5 more
wiley   +1 more source

Catching the spark: The role of electrodermal activity in understanding teacher enthusiasm and students' lesson enjoyment

open access: yesBritish Journal of Educational Technology, EarlyView.
Abstract Process‐oriented approaches are needed to understand the temporality and dynamics of teacher–student interactions in higher education classrooms. In this study, we follow a complexity science approach, based on non‐linear intra‐ and inter‐personal physiology methods, to explore the physiology of teacher–student interactions.
Muhterem Dindar   +3 more
wiley   +1 more source

Sexual function after prostate cancer surgery or radiotherapy in an international registry

open access: yesBJU International, EarlyView.
Objectives Our objective was to evaluate patient‐reported sexual function (SF) outcomes and sexual aid use 12 months after curative treatment for prostate cancer (PC). Patients & Methods This prospective registry‐based cohort study analysed men with localized or locally advanced PC enrolled in the TrueNTH Global Registry.
Y. Hess‐Busch   +10 more
wiley   +1 more source

The Early Upper Palaeolithic open‐air site of Friedrichsdorf‐Seulberg, Germany, in the context of the northern central European Aurignacian

open access: yesBoreas, EarlyView.
Our knowledge of the Early Upper Palaeolithic occupation in northern central Europe is very limited, and recent research at the open‐air site of Friedrichsdorf‐Seulberg in Hesse, Germany, provides important new information on the Aurignacian. The site is rather small (26.5 m2) and spatial analysis identified a central hearth with two associated ...
Tilman Böckenförde   +5 more
wiley   +1 more source

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