Results 101 to 110 of about 178,359 (292)

De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning

Advanced Science, EarlyView.
Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li, Haifan Gong, Yue Wang, Yinuo Zhao, Lixiang Li, Peijing Bao, Qingzhou Kong, Jialu Fu, Boyao Wan, Yumeng Zhang, Jinghui Zhang, Jiekun Ni, Zhongxue Han, Xueping Nan, Kunping Ju, Longfei Sun, Yuerui Ma, Huijun Chang, Mengqi Zheng, Yanbo Yu, Xiaoyun Yang, Xiuli Zuo, Haina Wang, Yanqing Li   +23 more
wiley   +1 more source

Ghost-free infinite derivative gravity

Journal of High Energy Physics, 2018
We present the construction of a gravitational action including an infinite series of higher derivative terms. The outcome is a classically consistent completion of a well-studied quadratic curvature theory.
Brage Gording, Angnis Schmidt-May
doaj   +1 more source

Hamiltonian dynamics and Noether symmetries in Extended Gravity Cosmology

, 2012
We discuss the Hamiltonian dynamics for cosmologies coming from Extended Theories of Gravity. In particular, minisuperspace models are taken into account searching for Noether symmetries.
A. Felice De, A. Vilenkin, A. Vilenkin, A. Vilenkin, A. Vilenkin, A. Vilenkin, A.A. Starobinsky, A.G. Riess, A.K. Sanyal, A.L. Berkin, B.S. DeWitt, C. Kiefer, C.G. Callan Jr., C.M. Will, C.W. Misner, C.W. Misner, C.W. Misner, C.W. Misner, C.W. Misner, C.W. Misner, D. Finkelstein, D. La, D.N. Spergel, E.E. Flanagan, G. Allemandi, G. Allemandi, G. Magnano, G. Magnano, G. Marmo, G. Vilkovisky, H. Everett, I. Hussain, I.L. Buchbinder, J. Bekenstein, J.A. Wheeler, J.B. Hartle, J.B. Hartle, J.B. Hartle, J.B. Hartle, J.B. Hartle, J.D. Logan, J.J. Halliwell, J.J. Halliwell, J.J. Halliwell, J.J. Halliwell, J.J. Halliwell, J.L. Synge, K. Maeda, K.A. Bronnikov, K.A. Bronnikov, K.A. Bronnikov, L. Amendola, M. De Laurentis, M. Jamil, M. Jamil, M. Milgrom, M.A. Lorentz, M.S. Madsen, N.A. Bahcall, N.A. Chernikov, N.D. Birrell, N.R. Napolitano, P. Teyssandier, P.J.E. Peebles, R. Arnowitt, R. Casadio, R. Kerner, R. Penrose, R. Ritis de, R.M. Wald, S. Basilakos, S. Capozziello, S. Capozziello, S. Capozziello, S. Capozziello, S. Capozziello, S. Capozziello, S. Capozziello, S. Capozziello, S. Capozziello, S. Capozziello, S. Capozziello, S. Capozziello, S. Capozziello, S. Capozziello, S. Capozziello, S. Capozziello, S. Capozziello, S. Capozziello, S. Capozziello, S. Capozziello, S. Capozziello, S. Capozziello, S. Capozziello, S. Capozziello, S. Capozziello, S. Capozziello, S. Capozziello, S. Capozziello, S. Capozziello, S. Cole, S. D. Odintsov, S. Gottlöber, S. Gottlöber, S. Nojiri, S. Nojiri, S. Nojiri, S. Nojiri, S. Weinberg, S.M. Carroll, S.M. Carroll, S.W. Hawking, T. Clifton, T. Padmanabhan, T.P. Sotiriou, T.P. Sotiriou, U. Seljak, V. Faraoni, V. Faraoni, V. Faraoni, V. Faraoni, V.I. Arnold, Y. Choquet-Bruhat   +122 more
core   +1 more source

Ultrasound Modulation of Visual Circuits in Mice Independent of Auditory Confound

Advanced Science, EarlyView.
In this study, Qiu et al. found that low‐intensity ultrasound can directly activate sparse ultrasound‐sensitive neurons (UNs) in the primary visual cortex (V1) of deafened mice. The proportion of these sparse UNs is pressure‐dependent. Furthermore, ultrasound modulates visual circuitry with distinct excitatory and inhibitory effects.
Jiaru He, Jiejun Zhu, Xinxin Wang, Zihao Chen, Jin Yang, Zhen Yuan, Hongzhi Xu, Lei Sun, Zhihai Qiu   +8 more
wiley   +1 more source

Sachs’ free data in real connection variables

Journal of High Energy Physics, 2017
We discuss the Hamiltonian dynamics of general relativity with real connection variables on a null foliation, and use the Newman-Penrose formalism to shed light on the geometric meaning of the various constraints.
Elena De Paoli, Simone Speziale
doaj   +1 more source

Photon‐Sphere Modes in Curved Optical Microcavities: A Black‐Hole Analogue Laser

Advanced Science, EarlyView.
An optical analogue of a Schwarzschild black hole is realized using curved microcavities that preserve light‐like geodesics. A new family of laser modes confined around the photon sphere is identified alongside conventional whispering‐gallery modes. Analytical theory, numerical simulations, and experiments reveal curvature‐induced confinement, enabling
Chenni Xu, Aswathy Sundaresan, Nazire‐Begüm Kazkal, Clement Lafargue, Lior Zarfaty, Li‐Gang Wang, Ofek Birnholtz, Dominique Decanini, Melanie Lebental, Patrick Sebbah   +9 more
wiley   +1 more source

Generalized covariant entropy bound in Einstein gravity with quadratic curvature corrections

Journal of High Energy Physics
We explore the generalized covariant entropy bound in the theory where Einstein gravity is perturbed by quadratic curvature terms, which can be viewed as the first-order quantum correction to Einstein gravity.
Hu Zhu, Jie Jiang
doaj   +1 more source

Universal spacetimes in four dimensions

Journal of High Energy Physics, 2017
Universal spacetimes are exact solutions to all higher-order theories of gravity. We study these spacetimes in four dimensions and provide necessary and sufficient conditions for universality for all Petrov types except of type II.
S. Hervik, V. Pravda, A. Pravdová
doaj   +1 more source

Nicotinamide and Pyridoxine Supplementation Enhances Muscle Stem Cell Activity and Muscle Regeneration in Humans: A Randomized Placebo‐Controlled Clinical Trial of High Force Eccentric Contraction Recovery in Healthy Young Men

Advanced Science, EarlyView.
In a randomized clinical trial, we test the potential of combined nicotinamide (NAM) and pyridoxine (PN) to improve muscle recovery through muscle stem cell (MuSC) activity. Daily oral NAM and PN supplementation after high intensity muscle contractions enhances MuSC activation and differentiation, and accelerates muscle regeneration, providing new ...
Grith Højfeldt, Joris Michaud, Ann Damgaard, Karoline Karlog, Eugenia Migliavacca, Sonia Karaz, Elham Pazirandeh‐Micol, Odd E. Johansen, Leonidas G. Karagounis, Bjørk W. Helge, William Hagemann, Michael Kjaer, Jerome N. Feige, Pascal Stuelsatz, Abigail L. Mackey   +14 more
wiley   +1 more source

Form factors, spectral and Källén-Lehmann representation in nonlocal quantum gravity

Journal of High Energy Physics
We discuss the conical region of convergence of exponential and asymptotically polynomial form factors and their integral representations. Then, we calculate the spectral representation of the propagator of nonlocal theories with entire form factors, in ...
Fabio Briscese, Gianluca Calcagni, Leonardo Modesto, Giuseppe Nardelli   +3 more
doaj   +1 more source