Results 31 to 40 of about 391,329 (357)
FEBS Letters, EarlyView.Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer +10 more
wiley +1 more source
Menorah Review (No. 60, Winter, 2004) [PDF]
, 2004 America and the Holocaust, Revisited: Notes on the Writing of ... -- The Road to Jewish Nationalism -- From the Classics -- The Reference Shell -- The Fundamentals of Fundamentalism -- From the Classics -- Hasidic Parables, Hasidic Polemics -- From the ...
core +1 more source
Classics in Neuroimaging: Development of PET Tracers for Imaging Monoamine Oxidases.
ACS Chemical Neuroscience, 2019 In this Viewpoint, we highlight the history of positron emission tomography (PET) radiotracer development to quantify changes in monoamine oxidase (MAO)-A and -B enzyme expression or activity.
Vidya Narayanaswami +7 more
semanticscholar +1 more source
Novel and unscrutinized immune entities of the zebrafish gut
FEBS Letters, EarlyView.Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil +5 more
wiley +1 more source
On closed-form optical solutions to the nonlinear model with the Kerr law nonlinearity
Results in Physics, 2023 The main contribution of this study is the application of a newly-proposed method to the Ginzburg–Landau equation arising from the propagation of nonlinear waves to obtain new closed-form optical solutions to this equation.
A. Althobaiti +3 more
doaj +1 more source
Dark Classics in Chemical Neuroscience: 3,4-Methylenedioxymethamphetamine.
ACS Chemical Neuroscience, 2018 Better known as "ecstasy", 3,4-methylenedioxymethamphetamine (MDMA) is a small molecule that has played a prominent role in defining the ethos of today's teenagers and young adults, much like lysergic acid diethylamide (LSD) did in the 1960s. Though MDMA
Lee E. Dunlap, A. Andrews, D. E. Olson
semanticscholar +1 more source
Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM
FEBS Letters, EarlyView.Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley +1 more source
FEBS Letters, EarlyView.Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi +5 more
wiley +1 more source
Lump solution and lump-type solution to a class of water wave equation
Results in Physics, 2023 In the field of nonlinear sciences, the theory of solitons has long been regarded as one of the most significant and effective areas of research. In this research field, there are many efficient techniques for solving partial differential equations.
S. Liu, Z. Yang, A. Althobaiti, Y. Wang
doaj +1 more source
FEBS Letters, EarlyView.Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer +7 more
wiley +1 more source