Results 31 to 40 of about 541,604 (319)

Dark Classics in Chemical Neuroscience: 3,4-Methylenedioxymethamphetamine.

ACS Chemical Neuroscience, 2018
Better known as "ecstasy", 3,4-methylenedioxymethamphetamine (MDMA) is a small molecule that has played a prominent role in defining the ethos of today's teenagers and young adults, much like lysergic acid diethylamide (LSD) did in the 1960s. Though MDMA
Lee E. Dunlap, A. Andrews, D. E. Olson
semanticscholar   +1 more source

Human colon organoid differentiation from induced pluripotent stem cells using an improved method

FEBS Letters, Volume 599, Issue 6, Page 912-924, March 2025.
We compared established protocols to differentiate induced pluripotent stem cells into colon organoids and found that activation of bone morphogenetic protein 2 signaling induced gene expression of colon‐specific markers. Adenovirus‐mediated transduction of the transcription factors HOXD13 or SATB2 further enhanced colonic gene expression, suggesting ...
I‐Ting Lee, Yu Takahashi, Takashi Sasaki, Yoshio Yamauchi, Ryuichiro Sato   +4 more
wiley   +1 more source

Re`class'ification of `quant'ified classical simulated annealing [PDF]

, 2008
We discuss a classical reinterpretation of quantum-mechanics-based analysis of classical Markov chains with detailed balance, that is based on the quantum-classical correspondence. The classical reinterpretation is then used to demonstrate that it successfully reproduces a sufficient condition for cooling schedule in classical simulated annealing ...
arxiv   +1 more source

Insights into the renal pathophysiology in Hermansky‐Pudlak syndrome‐1 from urinary extracellular vesicle proteomics and a new mouse model

FEBS Letters, Volume 599, Issue 7, Page 1055-1074, April 2025.
Hermansky‐Pudlak syndrome type 1 (HPS‐1) is a rare, autosomal recessive disorder with poorly understood renal involvement. Urinary extracellular vesicle (uEV) proteomics and a novel Hps1 mouse model reveal mitochondrial abnormalities and lipid accumulation in HPS‐1 kidney proximal tubule cells. Serum ApoA1 correlates with kidney function in our patient
Dawn M. Maynard, Bernadette R. Gochuico, Hadass Pri Chen, Christopher K. E. Bleck, Patricia M. Zerfas, Wendy J. Introne, William A. Gahl, May C. V. Malicdan   +7 more
wiley   +1 more source

Rediscovery and Canonization: The Roman Classics in the Middle Ages

Interfaces: A Journal of Medieval European Literatures, 2017
Issue 3 of Interfaces: A Journal of Medieval European Literatures explores the theme of the rediscovery and canonization of the Roman classics in medieval Western European literary culture, beginning in the eleventh century and reaching a wide impact on ...
Paolo Borsa, Christian Høgel, Lars Boje Mortensen, Elizabeth M. Tyler, Birger Munk Olsen, Jaakko Tahkokallio, Karin Margareta Fredborg, Monika Otter, Mia Münster-Swendsen, Wim Verbaal, Francine Mora, Venetia Bridges, Jean-Yves Tilliette, Filippo Bognini, Irene Salvo García, Marek Thue Kretschmer, Rita Copeland   +16 more
doaj   +1 more source

Classical communication and non-classical fidelity of quantum teleportation [PDF]

Quantum Inf Process 12, 3607 (2013), 2012
In quantum teleportation, the role of entanglement has been much discussed. It is known that entanglement is necessary for achieving non-classical teleportation fidelity. Here we focus on the amount of classical communication that is necessary to obtain non-classical fidelity in teleportation.
arxiv   +1 more source

The [2Fe‐2S] cluster of mitochondrial outer membrane protein mitoNEET has an O2‐regulated nitric oxide access tunnel

FEBS Letters, Volume 599, Issue 7, Page 952-970, April 2025.
The mitochondrial outer membrane iron–sulphur ([Fe‐S]) protein mitoNEET is a target of the type‐2 diabetes drug pioglitazone. Its unknown molecular function is linked to respiratory complex activity and mitochondrial function. We discovered that O2 protects the mitoNEET [2Fe‐2S] cluster against NO oxidation and desensitization towards reduction by H2S.
Thao Nghi Hoang, Meritxell Wu‐Lu, Alberto Collauto, Peter‐Leon Hagedoorn, Madalina Alexandru, Maike Henschel, Shahram Kordasti, Maria Andrea Mroginski, Maxie M. Roessler, Kourosh H. Ebrahimi   +9 more
wiley   +1 more source

Characteristics of the Kelch domain containing (KLHDC) subfamily and relationships with diseases

FEBS Letters, Volume 599, Issue 8, Page 1094-1112, April 2025.
The Kelch protein superfamily includes 63 members, with the KLHDC subfamily having 10 proteins. While their functions are not fully understood, recent advances in KLHDC2's structure and role in protein degradation have highlighted its potential for drug development, especially in PROTAC therapies.
Courtney Pilcher, Paula Armina V. Buco, Jia Q. Truong, Paul A. Ramsland, Monique F. Smeets, Carl R. Walkley, Jessica K. Holien   +6 more
wiley   +1 more source

Intellectual Sources of Historian's Legitimization - The Case of Gregory of Tours

Classica Cracoviensia, 2015
Intellectual Sources of Historian's Legitimization - The Case of Gregory of Tours The question of Gregory’s of Tours awareness of the persuasive potential of his learning he demonstrates in his works is discussed.
Kamil Choda
doaj   +1 more source

Interrelations between dualities in classical integrable systems and classical-classical version of quantum-classical duality [PDF]

Theoret. and Math. Phys., 222:2 (2025), 252-275
We describe the Ruijsenaars' action-angle duality in classical many-body integrable systems through the spectral duality transformation relating the classical spin chains and Gaudin models. For this purpose, the Lax matrices of many-body systems are represented in the multi-pole (Gaudin-like) form by introducing a fictitious spectral parameter.
arxiv   +1 more source