Results 41 to 50 of about 12,837 (265)
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Introduction: The Interpretation of Cultures at Fifty
Introducing the symposium “The Interpretation of Cultures at Fifty,” editors Andrea Cossu and Matteo Bortolini reflect on the dynamics of the iconicization of texts and the paradoxical quality of so-called “classics”: their being present while being ...
Andrea Cossu, Matteo Bortolini
doaj +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
“Orpheus’ Sermon”: Making a Case for an Antiquer Dickinson
The article discusses Dickinson as seizing upon the classics and the Latin language as correctives to the long lasting impact of Calvinism upon her cultural environment.
Eric Athenot
doaj +1 more source
1. A subject who has suffered from central serous chorio‐retinopathy in his left eye noticed differences in the colour of a given light as perceived by each eye alone. Standard screening tests (colour order and colour matching) indicated a tritan defect in the left eye; the right eye was normal on these tests.2.
Alpern, M., Kitahara, K., Krantz, D. H.
openaire +3 more sources
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
A review of the books: W. Friese et al. (eds.), Ascending and Descending the Acropolis: Movement in Athenian Religion; and T. Møbjerg et al. (eds.), The Hammerum Burial Site: Customs and Clothing in the Roman Iron Age (Aarhus: Aarhus University Press ...
Giorgio Baruchello
doaj +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Paraneoplastic Lupus Nephritis in a Child With Neuroblastoma Recurrence
Pediatric Blood &Cancer, EarlyView.
Gabriele Mortari +9 more
wiley +1 more source

