Results 91 to 100 of about 4,178,763 (294)
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Baillière's Clinical Rheumatology, 1994 Amyloidosis is a collective term for a heterogeneous group of disorders characterized by deposition of a fibrillar, proteinaceous material, amyloid, in various tissues and organs. Increasing knowledge about the different proteins that constitute the amyloid fibrils has made it possible to classify amyloidosis by the fibril protein, which appears more ...
openaire +3 more sources
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Inside the nation’s largest mental health institution: a prevalence study in a state prison system
BMC Public Health, 2017 Background The United States has the highest incarceration rate in the world which has created a public health crisis. Correctional facilities have become a front line for mental health care.
Tala Al-Rousan +4 more
doaj +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Perspectives for Revision of the ILO 2000 Classification of Radiographs [PDF]
cdc:131061Presentation at the NIOSH Scientific Workshop : Application of the ILO International Classification of Radiographs of Pneumoconioses to Digital Chest Radiographic Images (2008 : Mar 12-13 : Washington ...
core
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Non-probabilistic classification
, 1998 About the book: The book provides new developments in classification and data analysis, and presents new topics which are of central interest to modern statistics. In particular, these include classification theory, multivariate data analysis, multi-way
Gower, John C. +5 more
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iForest - Biogeosciences and Forestry, 2015 Greek fir (Abies cephalonica Loudon) grows in montane Mediterranean climates characterized by dry, warm summers. Drought is an important climatic feature of these montane ecosystems as it affects the floristic composition, structure and distribution of ...
Samaras Dimitrios A +3 more
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Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source