Molecular Oncology, EarlyView.PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham +21 more
wiley +1 more source
Impact of Land use on soil quality: Insights from the forest-savannah transition zone of Ghana
HeliyonLand use changes have a profound impact on soil fertility and agricultural production systems in the Forest-Savannah Transition Zone (FSTZ) of Ghana. Soil erosion and shortened fallow periods exacerbate soil fertility loss, further degrading soil quality.
Johnny Kofi Awoonor +4 more
doaj +1 more source
A toolbox for brain network construction and classification (BrainNetClass)
, 2020 Zhen Zhou +9 more
openalex +1 more source
Mitosis‐Karyorrhexis Index evaluation by digital image visual analysis for application of International Neuroblastoma Pathology Classification in FNA biopsy [PDF]
, 2021 Neha Bhardwaj +5 more
openalex +1 more source
Decrypting cancer's spatial code: from single cells to tissue niches
Molecular Oncology, EarlyView.Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik +4 more
wiley +1 more source
Towards a Consensus on an ICF-Based Classification System for Horizontal Sound-Source Localization [PDF]
, 2022 Griet Mertens +7 more
openalex +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
A time series classification approach to non-destructive hardness testing using magnetic Barkhausen noise emission [PDF]
, 2021 Martin Unterberg +3 more
openalex +1 more source
Molecular Oncology, EarlyView.A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira +14 more
wiley +1 more source
A Convolutional Neural Network Based Auto Features Extraction Method for Tea Classification with Electronic Tongue [PDF]
, 2019 Yuanhong Zhong +7 more
openalex +1 more source