Results 91 to 100 of about 1,014,031 (308)
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Energy Efficient Hardware Accelerators for Packet Classification and String Matching [PDF]
, 2010 This thesis focuses on the design of new algorithms and energy efficient high throughput hardware accelerators that implement packet classification and fixed string matching.
Kennedy, Alan
core
Robust Sound Event Classification using Deep Neural Networks [PDF]
, 2015 The automatic recognition of sound events by computers is an important aspect of emerging applications such as automated surveillance, machine hearing and auditory scene understanding.
Song, Yan +4 more
core +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Applied SciencesPredicting innovation outcomes at the firm level continues to be an important but challenging goal for researchers and practitioners alike. In this study, multiple machine learning models, encompassing both ensemble-based and single-model approaches ...
Marko Martinović +2 more
doaj +1 more source
Predicting sample size required for classification performance
BMC Medical Informatics and Decision Making, 2012 Background Supervised learning methods need annotated data in order to generate efficient models. Annotated data, however, is a relatively scarce resource and can be expensive to obtain.
Figueroa Rosa L +3 more
doaj +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
ANN vs. SVM : which one performs better in classification of MCCs in mammogram imaging
, 2012 Classification of microcalcification clusters from mammograms plays essential roles in computer-aided diagnosis for early detection of breast cancer, where support vector machine (SVM) and artificial neural network (ANN) are two commonly used techniques.
Jinchang Ren, Ren, Jinchang
core +1 more source
Performance of CellaVision DM96 in leukocyte classification
Journal of Pathology Informatics, 2013 Background: Leukocyte differentials are an important component of clinical care. Morphologic assessment of peripheral blood smears (PBS) may be required to accurately classify leukocytes. However, manual microscopy is labor intensive.
Lik Hang Lee +5 more
doaj +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source