Results 181 to 190 of about 1,373,879 (350)

Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis

Molecular Oncology, EarlyView.
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht, Sameer Gupta, Amrita Chaurasia, Manisha Sachan   +3 more
wiley   +1 more source

Improving Accuracy and Speed of Optimum-Path Forest Classifier Using Combination of Disjoint Training Subsets

, 2011
The Optimum-Path Forest (OPF) classifier is a recent and promising method for pattern recognition, with a fast training algorithm and good accuracy results.
Ponti-, Moacir P., Sansone, C., Kittler, J., Roli, F., Papa, Joao P. [UNESP]   +4 more
core  

Diffusion Classifier Guidance for Non-robust Classifiers

Classifier guidance is intended to steer a diffusion process such that a given classifier reliably recognizes the generated data point as a certain class. However, most classifier guidance approaches are restricted to robust classifiers, which were specifically trained on the noise of the diffusion forward process. We extend classifier guidance to work
Philipp Väth, Dibyanshu Kumar, Benjamin Paassen, Magda Gregorová   +3 more
openaire   +3 more sources

Measures of Diversity in Classifier Ensembles and Their Relationship with the Ensemble Accuracy

Machine-mediated learning, 2003
L. Kuncheva, C. J. Whitaker
semanticscholar   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Building Classifier Ensembles Using Greedy Graph Edit Distance

, 2015
Classifier ensembles aim at more accurate classifications than single classifiers. In the present paper we introduce a general approach to building structural classifier ensembles, i.e. classifiers that make use of graphs as representation formalism. The
Fischer, Andreas, Riesen, Kaspar, Ferrer, Miquel   +2 more
core  

Adversarial CAM Guidance for Chest X-Ray Classification: Reducing Framing Sensitivity with Mask Supervision. [PDF]

Biomimetics (Basel)
Batchuluun G, Lee SJ, Im SJ, Park KR.
europepmc   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Evaluating ensemble learning approaches for horizontal gene transfer detection. [PDF]

Sci Rep
Wijaya AJ, Anžel A, Hattab G.
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source