Results 61 to 70 of about 1,065,063 (179)
A Formal ORM-to -UML Mapping Algorithm [PDF]
The object-role model (ORM) data structure can be represented in the unified modeling language (UML) using the five fact encoding constructs: class attribute, association, association class, sub-class and the association qualifier.
Bollen,Peter
core +1 more source
Selective targeting of cortactin tandem repeat acetylation by human lysine deacetylases
The FEBS Journal, EarlyView.Cortactin function is regulated by acetylation at several lysine residues within its tandem repeat region. Using genetic code expansion to generate cortactin variants containing precisely defined acetylation marks, we show that HDAC6 is the primary enzyme removing these modifications, with SIRT1 and SIRT2 also acting at selected sites but with lower ...
Jan Komarek +12 more
wiley +1 more source
The FEBS Journal, EarlyView.Ferroptosis is driven by unrestricted peroxidation of polyunsaturated fatty acyl (PUFA) chains in membrane phospholipids. In triple‐negative breast cancer cells, lipid droplets (LDs) sequester dietary PUFAs, limiting their incorporation into membrane phospholipids, preventing mitochondrial damage, and reducing lipid peroxidation and ferroptosis.
Ana Kump +10 more
wiley +1 more source
The FEBS Journal, EarlyView.TGF‐β signaling regulates extracellular vesicle (EV) release in cancer cells by modulating the expression and activity of genes associated with EV biogenesis. The TGF‐β‐induced upregulation of RAB4A expression facilitates fast endosomal recycling, a process that limits the fusion of multivesicular bodies with the plasma membrane and EV secretion. Hence,
Dorival Mendes Rodrigues‐Junior +5 more
wiley +1 more source
Improving the Usability of OCL as an Ad-hoc Model Querying Language [PDF]
, 2013 . The OCL is often perceived as difficult to learn and use. In previous research, we have defined experimental query languages exhibiting higher levels of usability than OCL.
Störrle, Harald
core +1 more source
Long‐read sequencing‐based atlas of tissue‐specific expression of DNM1L transcript variants
The FEBS Journal, EarlyView.Targeted long‐read sequencing resolves full‐length DNM1L (Drp1) isoforms and reveals conserved, tissue‐specific expression patterns across human and mouse tissues. Functional assays show that Drp1 isoforms differ in their ability to drive mitochondrial fission, independent of abundance, with specific exons modulating activity.
Feng Yan +19 more
wiley +1 more source
Metroeconomica, EarlyView.ABSTRACT We propose a demand‐led heterogeneous firm macroeconomic model to study the impact of an exchange rate devaluation on output and financial stability. We simulate the model and find that, in the presence of foreign debt, a devaluation can have contractionary effects.
Lucca Gustafson Rodrigues +2 more
wiley +1 more source
The performance of artificial intelligence-driven technologies in diagnosing mental disorders: an umbrella review. [PDF]
NPJ Digit Med, 2022 Abd-Alrazaq A +7 more
europepmc +1 more source
MDA: correctness of model transformations. Which models are schemas? [PDF]
, 2005 How to determine, is a proposed model transformation correct, or not? In general, the answer may depend on the model semantics. Of course, a model transformation is “correct”, if we can extend it to a “correct” instance data transformation.
Podnieks, Karlis
core
Large Language Models for Explainable Medical Text Summarization: A Systematic Literature Review
WIREs Data Mining and Knowledge Discovery, Volume 16, Issue 2, June 2026.The graphical abstract highlights the three key aspects addressed in this review: the technical background of medical text summarization methods relevant to clinical decision support; the LLM background in providing context for its diagnosis and clinical significance; and clinical decision support with summarization and explainability in patient care ...
Aleka Melese Ayalew +3 more
wiley +1 more source