Results 71 to 80 of about 7,673,289 (336)

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

DOMESTIC DEMAND ANALYSIS FOR THE AVAILABILITY OF CLEAN WATER AT MAULAFA DISTRICT

Jurnal Teknik Sipil, 2022
The rapid population growth of an area is usually followed by an increase in water demand. The current availability of water is not necessarily able to meet the increasing demand for clean water.
Fransiska C.N. Harmans, Agustinus H. Pattiraja, Oktovianus E. Semiun   +2 more
doaj   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Surface damage reduction effect of ultra-high working face in Shangwan coal mine

Scientific Reports
Green mining is the basic background of high-quality mining, and source reduction is the most important part, among which the optimization of working face height and length is the most active.
L. I. U. Xinjie, Yang Yingming, Zhao Yongqiang, WANG Xiaolong, Liu Gang, Xu Zhuhe   +5 more
doaj   +1 more source

Vertical zoning characteristics and genesis mechanism of groundwater hydrochemistry: a case study of Xinjie Mining Area

Meitan kexue jishu
Mine water, as the main potential water supply source for coal mine sites, has a good potential for comprehensive reuse. However, the complex and diverse physical and chemical reactions between the coal seam roof-filling aquifers and the surrounding ...
Xudong WANG, Zuyu YAN, Qiang GUO, Suo ZHANG, Jiawei TANG, Yutian HU, Xiaoqing LIU, Jingfeng LI   +7 more
doaj   +1 more source

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

Molecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon, Moa Stenudd, Margherita Zamboni, Kanar Alkass, Carl‐Johan Eriksson, Lars Pedersen, Alrik Schörling, Anna Thoss, Anders Bergh, Pernilla Wikström, Hans‐Olov Adami, Henrik Toft Sørensen, Henrik Druid, Jonas Frisén   +13 more
wiley   +1 more source

Local Land Use: Decision Expands Federal Government\u27s Role [PDF]

, 2003
The United States Environmental Protection Agency (EPA), pursuant to its authority under the Clean Water Act, has promulgated regulations creating the Storm Water Management Program.
Nolon, John R.
core   +1 more source

Enhanced removal of refractory organic pollutants from high-salinity mining wastewater by E-peroxone process

Meitan xuebao
High-salinity mining wastewater is produced in the process of zero discharge. Due to its complex composition and high organic concentration, its treatment has become a worldwide problem.
Anni CHEN, Qiang GUO, Yanying YIN, Jingfeng LI, Yixiang BAO, Min WU, Shizuo YI, Jianbing WANG, Huijiao WANG   +8 more
doaj   +1 more source

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

Molecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova, Marketa Pavlikova, Lucie Pifkova, Robin Jugas, Tana Machackova, Lenka Radova, Milana Sachlova, Renata Bartosova, Tetiana Samoilenko, Zuzana Feckova, Jana Orlickova, Erika Slamova, Elleni Ponechal Michu, Dagmar Al Tukmachi, Michaela Ruckova, Martina Vodinska, Jan Kotoucek, Tina Catela Ivkovic, Marie Boudna, Lucia Bohovicova, Teodor Stanek, Jana Halamkova, Martin Svoboda, Vladimir Prochazka, Tomas Grolich, Zdenek Kala, Ondrej Slaby   +26 more
wiley   +1 more source

The Economic Argument for Cleaning Up the Chesapeake Bay and its Rivers [PDF]

, 2012
Failure to "Save the Bay" threatens the Bay's value as an economic driver. Conversely, investing in clean-water technology creates jobs, generates economic activity, and saves money in the long run. Hence, the protection and restoration of the Chesapeake
Tom Pelton
core