Results 31 to 40 of about 1,020,281 (333)

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Valuation of Ecosystem Services from Wetlands Mitigation in the United States

Land, 2015
Section 404 of the U.S. Clean Water Act includes most wetlands in its jurisdiction and requires wetland mitigation to compensate for permitted wetland losses.
Naveen Adusumilli
doaj   +1 more source

Examining impacts of policy, technology, and climate extremes on thermoelectric power production and river thermal pollution in the Midwest and Northeast of the United States

Frontiers in Environmental Science, 2023
As one of the components comprising food-energy-water systems (FEWS), the energy sector, especially electricity production, is intimately connected to water.
Jiaqi Zhang, Mengye Chen, Shang Gao, Zhi Li, Charles J. Vörösmarty, Charles J. Vörösmarty, Charles J. Vörösmarty, Balazs Fekete, Balazs Fekete, Ariel Miara, Yang Hong   +10 more
doaj   +1 more source

Mississippi River Water Quality and the Clean Water Act: Progress, Challenges, and Opportunities [PDF]

, 2007
Makes recommendations for how to coordinate water quality monitoring efforts among the ten states through which the Mississippi River runs.

core  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Microfluidic electro‐viscoelastic manipulation of extracellular vesicles

FEBS Open Bio, EarlyView.
The electro‐viscoelastic manipulation as a potential method for separation of particles based on size. The particles introduced as a sheath flow migrate to the channel center under the influence of simultaneously applied electric field and pressure driven flow.
Seyedamirhosein Abdorahimzadeh, Éva Bozó, Zikrullah Bölükkaya, Artem Zhyvolozhnyi, Anatoliy Samoylenko, Henrikki Liimatainen, Seppo J. Vainio, Caglar Elbuken   +7 more
wiley   +1 more source

Benthic algae assessments in the EU and the US: Striving for consistency in the face of great ecological diversity

Ecological Indicators, 2021
Freshwaters face multiple environmental problems including eutrophication, acidification, salinization, and climate-change, all of which can lead to impairment of ecosystem structure and function.
Donald F. Charles, Martyn G. Kelly, R. Jan Stevenson, Sandra Poikane, Susanna Theroux, Aleksandra Zgrundo, Marco Cantonati   +6 more
doaj   +1 more source

The \u27Ascent of Man\u27: Legal Systems and the Discovery of an Environmental Ethic [PDF]

, 1998
A decade ago, firefighters in a warehouse on the Rhine in Switzerland washed chemicals, solvents, and mercury into the river, destroying all life in the river for miles, killing millions of fish, and endangering the water supplies of cities in Germany ...
Robinson, Nicholas A.
core   +1 more source

An evaluation of metal removal during wastewater treatment: The potential to achieve more stringent final effluent standards [PDF]

, 2011
This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ 2011 Taylor & Francis.Metals are of particular importance in relation to water quality, and concern regarding the impact of these ...
Arundel J., Barnes D., Barth E. F., Birkett J. W., Brown H. G., Chen K. Y., Cheng M. H., D. Ziolko, Davis J. A., Eckenfelder W. W., Esmond S. E., Fatoki O. S., Gray N. F., Groombridge B., Hawksworth D. L., Henson M. C., J. N. Lester, Klein L. A., Koch C. M., Koch M., Landner L., Landner L., Lawson P. S., Le Quesne T., Lester J. N., Lester J. N., Lester J. N., Lester J. N., Lester J. N., Liu Y., M. D. Scrimshaw, Malaney G. W., Mowat A., Neufeld R. D., Neufeld R. D., O. V. Martin, Raposo J. C., Reid W., Roberts P., Rossin A. C., Rudd T., Rule K. L., Spath R., Stander L., Stasinakis A. S., Stonebrook H., Stover R. C., Takiguchi M., Tomlinson T. G., Verma M. M., Yeoman S.   +50 more
core   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source