Results 31 to 40 of about 14,551 (299)

Targeted next-generation sequencing of dedifferentiated chondrosarcoma in the skull base reveals combined TP53 and PTEN mutations with increased proliferation index, an implication for pathogenesis [PDF]

open access: yes, 2016
Dedifferentiated chondrosarcoma (DDCS) is a rare disease with a dismal prognosis. DDCS consists of two morphologically distinct components: the cartilaginous and noncartilaginous components.
Cao, Dengfeng   +13 more
core   +2 more sources

A comparison of patient testimonials on YouTube of the most common orthodontic treatment modalities: braces, in-office aligners, and direct-to-consumer aligners [PDF]

open access: yes, 2020
Introduction: The objectives of this research was to investigate and compare the educational value of the most popular YouTube orthodontic patient testimonials between braces (B), in- office aligners (IOA), and direct-to-consumer aligners (DTCA), and to ...
Hunsaker, Riley
core   +1 more source

Effects of variable attachment shapes and aligner material on aligner retention. [PDF]

open access: yes, 2016
OBJECTIVE: To evaluate the retention of four types of aligners on a dental arch with various attachments. MATERIALS AND METHODS: For this study, three casts were manufactured, two of which contained attachments (ellipsoid and beveled), and one without ...
Asatrian G   +5 more
core   +1 more source

In vivo E2F reporting reveals efficacious schedules of MEK1/2–CDK4/6 targeting and mTOR–s6 resistance mechanisms [PDF]

open access: yes, 2018
Targeting cyclin-dependent kinases 4/6 (CDK4/6) represents a therapeutic option in combination with BRAF inhibitor and/or MEK inhibitor (MEKi) in melanoma; however, continuous dosing elicits toxicities in patients. Using quantitative and temporal in vivo
Aplin, Andrew E.   +14 more
core   +1 more source

Patients Preference to Clear Aligner Therapy Over Conventional Orthodontic Therapy

open access: yesInternational Journal of Research in Pharmaceutical Sciences, 2020
Malocclusion is defined as irregularity of the teeth or a mal-relationship of the dental arches beyond the range of what is accepted as normal occlusion. Maloccluded teeth can cause psychological problems that are related to impaired dentofacial esthetics. Malocclusion may also cause serious problems related to oral health.
null Harippriya Karthikeyan   +2 more
openaire   +1 more source

Two-year follow-up of macaques developing intermittent control of the human immunodeficiency virus homolog simian immunodeficiency virus SIVmac251 in the chronic phase of infection [PDF]

open access: yes, 2015
Off-therapy control of viremia by HIV-infected individuals has been associated with two likely players: a restricted viral reservoir and an efficient cell-mediated immune response.
Arts, Eric   +14 more
core   +2 more sources

In vitro cytotoxicity of different thermoplastic materials for clear aligners [PDF]

open access: yes, 2019
To investigate the in vitro cytotoxicity of different thermoplastic materials for clear aligners on human primary gingival fibroblasts (HGFs)
Bucci, Rosaria   +5 more
core   +1 more source

Do the Mechanical and Chemical Properties of Invisalign\u3csup\u3eTM\u3c/sup\u3e Appliances Change After Use? A Retrieval Analysis [PDF]

open access: yes, 2016
Aim: To investigate the mechanical and chemical alterations of Invisalign appliances after intraoral aging. Materials and methods: Samples of Invisalign appliances (Align Technology, San Jose, California, USA) were collected following routine treatment ...
Bradley, T. Gerard   +4 more
core   +1 more source

Chromosomal instability in untreated primary prostate cancer as an indicator of metastatic potential. [PDF]

open access: yes, 2020
BackgroundMetastatic prostate cancer (PC) is highly lethal. The ability to identify primary tumors capable of dissemination is an unmet need in the quest to understand lethal biology and improve patient outcomes.
Cadaneanu, Radu M   +14 more
core  

Mass Azithromycin Distribution and Community Microbiome: A Cluster-Randomized Trial. [PDF]

open access: yes, 2018
BackgroundMass distributions of oral azithromycin have long been used to eliminate trachoma, and they are now being proposed to reduce childhood mortality. The observed benefit appears to be augmented with each additional treatment, suggesting a possible
Amza   +28 more
core   +1 more source

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