Results 101 to 110 of about 5,441 (291)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Comparison of fixed braces and clear braces for malocclusion treatment

open access: yesBMC Oral Health
Background To study and compare the effects of clear aligners without brackets and traditional fixed aligners in orthodontic treatment. Methods The samples were collected from January 2022 to April 2023.
Fan Liu   +4 more
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Dental arches and occlusion correction possibilities with clear aligners

open access: yes, 2017
Threatment with thermoplastic aligners is relatively new in the history of orthodontic treatment, that is why many doctors evaluate this treatment method controversially.
Kaukaitė, Laura
core  

Awareness and prevalence of orthodontic clear aligners

open access: yes, 2019
Tilgangur: Megin markmið rannsóknarinnar var að afla upplýsinga um hvort tannlæknar og sérfræðingar hér á landi noti tannréttingaskinnur sem meðferðarlausn. Þessari tannréttinga aðferð hefur verið beitt erlendis síðustu ár.
Jóney Ósk Sigurjónsdóttir 1994-
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Youth Perception of Different Orthodontic Appliances

open access: yesPatient Preference and Adherence, 2020
Reem A Alansari Department of Orthodontics, Faculty of Dentistry, King Abdulaziz University, Jeddah, Saudi ArabiaCorrespondence: Reem A AlansariDepartment of Orthodontics, Faculty of Dentistry, King Abdulaziz University, Jeddah 21589, Saudi ArabiaEmail ...
Alansari RA
doaj  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Comparative evaluation of the effect of different cleaning agents on colour and surface roughness of Invisalign clear aligners: a cross-over randomized controlled trial

open access: yesBMC Oral Health
Background Recent advancements in orthodontics have led to the widespread use of clear aligners, appreciated for their aesthetic and comfort advantages.
Banu Kılıç   +2 more
doaj   +1 more source

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