Results 151 to 160 of about 2,976,973 (351)

A MOSAIC of methods: Improving ortholog detection through integration of algorithmic diversity

, 2014
Ortholog detection (OD) is a critical step for comparative genomic analysis of protein-coding sequences. In this paper, we begin with a comprehensive comparison of four popular, methodologically diverse OD methods: MultiParanoid, Blat, Multiz, and OMA ...
Hernandez, Ryan D., Maher, M. Cyrus
core   +2 more sources

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Comparative evaluation of the effect of different cleaning agents on colour and surface roughness of Invisalign clear aligners: a cross-over randomized controlled trial

BMC Oral Health
Background Recent advancements in orthodontics have led to the widespread use of clear aligners, appreciated for their aesthetic and comfort advantages.
Banu Kılıç, Şeymanur Canpolat, Merve Öztürk   +2 more
doaj   +1 more source

A Comparative Study on the Efficiency of Clear Aligners Versus Conventional Braces in Adult Orthodontic Patients

Journal of Pharmacy and Bioallied Sciences
Background: Orthodontic treatment in adults has gained popularity with the advent of clear aligners as an alternative to conventional braces. Materials and Methods: A total of 100 adult patients requiring orthodontic treatment were enrolled in this study
Mohammad K. Alam, Mohammad Y. Hajeer, Miad A. Alahmed, Sadeem M. Alrubayan, Maram F. Almasri   +4 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Evaluation of Antimicrobial Effect of Biologically Safe Selenium Nanoparticles-coated Clear Aligner—An In vitro Study

Journal of Indian Orthodontic Society
Objective To synthesize selenium nanoparticles (SeNPs) from plant extract, characterize them, coat them on clear aligners, and evaluate their cytotoxicity and antimicrobial activity.
Hemamalini D, Priya Riona Mary, Shahul Hameed Faizee KM, Xavier Dhayananth   +3 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Assessment of Patient-Reported Outcomes in the Use of Clear Aligners Compared to Conventional Fixed Braces

Journal of Pharmacy and Bioallied Sciences
Introduction: This study aims to compare patient-reported outcomes (PROs) between clear aligners and conventional fixed braces. Orthodontic treatments not only focus on functional outcomes but also patient satisfaction, comfort, and aesthetics ...
Kakarla Subbaraju, Jashan Deep Goyal, Vijeta Patri, Pragyna Panigrahi, Mahishi G. Suthar, Praveen Kumar Varma, Afreen Kauser   +6 more
doaj   +1 more source

An optofluidic router in a low-cost (PDMS) platform for rapid parallel sample analysis [PDF]

, 2016
En col·laboració amb la Universitat de Barcelona (UB), la Universitat Autònoma de Barcelona (UAB) i l'Institut de Ciències Fotòniques (ICFO)Optofluidic system for (bio)chemical applications are becoming more demanding in terms of num- ber of control ...
Goyvaerts, Jeroen
core   +1 more source

A Cross‐Sectional Survey of the Use of Clear Aligners by General Dentists in Australia

Clinical and Experimental Dental Research
The primary aim of the investigation was to survey clear aligner therapy (CAT) use among general dentists in Australia. A secondary aim was to evaluate the factors that influenced general dentists in Australia not to provide CAT.
Maurice J Meade, T. Weir
semanticscholar   +1 more source