Results 191 to 200 of about 2,666,153 (370)

Evaluation of mandibular motion in adolescents with skeletal class II division 1 malocclusion during mandibular advancement using clear functional aligners: a prospective study [PDF]

Qiuyue Wu, Yueying Zhang, Hua Xiao, Jiajing Zheng, Tianlu Jiang, Yusen Du, Meng Cao, Feifei Li   +7 more
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Effect of clear aligner type on maxillary full-arch intrusion: 3D analysis using finite element method

BMC Oral Health
Background Vertical maxillary excess (VME) is one of the most common reasons for seeking orthodontic treatment. Total intrusion with aligners is a promising alternative to surgery in some cases. Considering the elastic deformation of aligners, this study
Allahyar Geramy, Fatemeh Safari
doaj   +1 more source

Comparison of gap width of thermoformed clear aligners produced by different 3D printers

Brazilian Dental Science
Background: Although clear aligners have been widely used in orthodontics, factors such as thickness and fit are still little studied. In addition, other clinical aspects, such as optical properties, forces and moments and predictability of movement ...
Murilo Matias, Eduardo Listik, Vania Heidorn, Elaine Carvalho de Souza, Cristiane Aparecida da Silva Rios, Jessica Mayara Arcanjo, Louise Marie Gouvea Pierard, Thalita Sales Fontes, Ana Carla Raphaelli Nahas   +8 more
doaj   +1 more source

Accuracy of Invisalign Progress Assessment with Clear Aligners: A Retrospective Study

, 2022
Bo Li, Yi-Meng Xu, Rui-Ying Shi, Yi-Rong Hu, Siying Liu, Zexu Gu, P Cardoso, D Espinosa, P Mecenas, C Flores-Mir, D Normando, T Weir, K Harris, K Ojima, C Dan, M Upadhyay, A Alshehri, C Kuo, . Nanda, R, C Aman, B Azevedo, E Bednar, S Chandiramami, D German, E Nicholson, . Scarfe, W, V Gandhi, S Mehta, M Gauthier, J Mu, C Kuo, R Nanda, S Yadav, G Rossini, S Parrini, T Castroflorio, A Deregibus, C Debernardi, D Baldwin, G King, D S Ramsay, N Haouili, N Kravitz, N Vaid, D Ferguson, L Makki, N Kravitz, B Kusnoto, E Begole, A Obrez, B Agran, N Kravitz, B Kusnoto, B Agran, G Viana, M Simon, L Keilig, J Schwarze, B Jung, C Bourauel, R Mclaughlin, J Bennett, G Vasilakos, R Schilling, D Halazonetis, N Gkantidis, L Lemos, I Rebello, C Vogel, M Barbosa, B Sayania, M Merchant, P Josephs, C Chung, T Flgge, S Schlager, K Nelson, S Nahles, M Metzger, C Keul, J Gth, M Aragn, L Pontes, L Bichara, C Flores-Mir, D Normando, O Charalampakis, A Iliadi, H Ueno, D Oliver, K Kim, G Chen, S Chen, X Zhang, R Jiang, Y Liu, F Shi, T Xu   +99 more
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

Effects of clear aligners on the vertical position of the molar teeth and the vertical and sagittal relationships of the face: a preliminary retrospective before-after clinical trial [PDF]

Mehrnaz Moradinejad, Ricky E. Harrell, Seyyed Mohammad Mousavi, M Jafarpour Alavi, Alireza Darvish Basseri, Arman Feiz, Hanie Daryanavard, Vahid Rakhshan   +7 more
openalex   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Non-surgical Treatment of a Late Adolescent Patient with Skeletal Class II Malocclusion Using Clear Aligners: A Case Report [PDF]

, 2022
Lindsay Robertson, Tarek El‐Bialy
openalex   +1 more source