Results 61 to 70 of about 1,756,744 (248)
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Scientific ReportsPassive non-destructive evaluation tools such as acoustic emission (AE) testing and acousto-ultrasonics (AU) approach present a complex problem in damage localisation in complex and nonhomogeneous geometries. A novel AU-guided AE frequency interpretation
Claudia Barile +7 more
doaj +1 more source
Open bite treatment using clear aligners.
, 2013 A 35-year-old female patient with dentoalveolar open bite of 4 mm, molar Class I malocclusion, centered midlines, moderate crowding, and labial inclination of the lower incisor was treated with clear aligners to reduce protrusion and close the anterior ...
OLIVERIO, Teresa +4 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Orthodontic treatment of class three malocclusion using clear aligners: A case report
Journal of Oral Biology and Craniofacial Research, 2019 Class III malocclusion is a growth-related challenging condition for orthodontists. We present a case of a 11-year-old girl with a skeletal class III malocclusion with bilateral cross bite, and a functional shift of the lower dental midline. A multiphase
Edoardo Staderini +2 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Progress in OrthodonticsObjectives To quantitatively compare the orthodontic forces exerted during mandibular incisor retraction by Perfitalign 4D aligners and thermoformed aligners over a 60-hour dynamic monitoring period, assess tooth movement trends, and investigate the ...
Jianing Xu +5 more
doaj +1 more source
Accuracy and Stability of Clear Aligner Treatment: A Systematic Review
Journal of Pharmacy and Bioallied SciencesThis systematic review evaluates the long-term stability and retention of clear aligner treatment, focusing on factors like aligner compliance, attachment use, and treatment duration.
V. Vigneshkumar +6 more
doaj +1 more source