Results 181 to 190 of about 250,661 (348)

Clear-Cell Renal Cell Carcinoma Molecular Subtypes Differ by African and European Genetic Similarity [PDF]

Roy Elias, Thomas R. Nirschl, Michael E. Rezaee, Anirudh Yerrapragada, Shirley Wang, Joseph Cheaib, Ridwan Alam, Sunil Patel, Yuezhou Jing, Mohamad E. Allaf, David McKean, Alison P. Klein, Elana J. Fertig, Ezra Baraban, Yasser Ged, Srinivasan Yegnasubramanian, Nirmish Singla   +16 more
openalex   +1 more source

Tumor-associated macrophages in clear cell renal cell carcinoma express both gastrin-releasing peptide and its receptor: a possible modulatory role of immune effectors cells [PDF]

, 2009
Jens Bedke, Bernhard Hemmerlein, Christina Perske, Andreas J. Gross, Markus Heuser   +4 more
openalex   +1 more source

Preliminary exploration of the putative function of SF3A2 in clear cell renal cell carcinoma. [PDF]

Mol Med Rep
Chen R, Xu J.
europepmc   +1 more source

DNMT2‐m5C‐ACLY Axis Promotes Lenvatinib Resistance in Hepatocellular Carcinoma Through Histone Acetylation‐Mediated Notch Pathway

Advanced Science, EarlyView.
Lenvatinib resistance poses a major challenge in advanced hepatocellular carcinoma (HCC). This study reveals that DNMT2 upregulation is a key driver, which stabilizes ACLY mRNA via m5C modification and activates the Notch signaling pathway. Crucially, combining ACLY inhibitors with lenvatinib overcomes resistance and suppresses tumors, offering a ...
Shiguang Yang, Jie Li, Shengwei Mao, Xuhui Zhao, Douwaner Liu, Jiafeng Chen, Jialu Fu, Yichao Bu, Xiaoling Wu, Shaoqing Liu, Qifeng Yu, Qiongzhu Dong, Zheng Tang, Yuan Fang, Yinghong Shi   +14 more
wiley   +1 more source

CDCA5-EEF1A1 interaction promotes progression of clear cell renal cell carcinoma by regulating mTOR signaling [PDF]

Xun Wang, An Shi, Jie Liu, Wen Kong, Yiran Huang, Wei Xue, Fan Yang, Jiwei Huang   +7 more
openalex   +1 more source

Clear Cell Renal Cell Carcinoma Metastasis to the Thyroid: A Narrative Review of the Literature. [PDF]

Cancers (Basel)
Samaras MG, Pouliakis A, Skaretzos K, Boutas I, Kontogeorgi A, Dimas DT, Ieronimaki AI, Zanelli M, Palicelli A, Zizzo M, Broggi G, Caltabiano R, Salzano S, Koufopoulos NI.   +13 more
europepmc   +1 more source

GALNT10 Affects O‐Glycosylation of IGFBP7 to Promote Tumor Vascular Remodeling and Metastasis of Ovarian Cancer

Advanced Science, EarlyView.
The glycosyltransferase GALNT10 facilitates ovarian cancer metastasis through the induction of tumor cell EMT and tumor vascular dysfunction. GALNT10 enhanced the extracellular secretion of IGFBP7 through O‐GalNAc glycosylation modification at the T188 site, which subsequently interacts with CD93 on endothelial cells, leading to vascular remodeling ...
Yanan Zhang, Ayala Zuha, Zhangxin Wu, Aiping Luo, Bixia Jin, Qinkun Sun, Yuan Li, Qiyu Liu, Hongyan Guo, Chunliang Shang   +9 more
wiley   +1 more source

Liquid Biopsy in Clear Cell Renal Cell Carcinoma: Diagnostic Potential of Urinary miRNAs. [PDF]

Cancers (Basel)
Vannuccini G, Paladini A, Mearini M, Cocci F, Giardino G, Mangione P, Maulà V, Mirra D, Mearini E, Cochetti G.   +9 more
europepmc   +1 more source

The FOXC2‐LAMA4 Axis Orchestrates Vasculogenic Mimicry and Immunosuppressive Niche Formation to Drive Metastatic Cascade in Renal Cell Carcinoma

Advanced Science, EarlyView.
Advanced clear cell renal cell carcinoma metastasis is driven by a FOXC2+ tumor subpopulation. These cells execute vasculogenic mimicry for dissemination and secrete LAMA4. LAMA4 engages macrophage ITGA6, activating the STAT6/GATA3 axis to polarize macrophages into a pro‐metastatic, immunosuppressive phenotype.
Jiaxi Yao, Tong Xu, Chengyuan Wang, Chenyuan Wang, Junfeng Xie, Rui Zheng, Ke Wang, Xingzuo Jiang, Zewei Hu, Hongwei Jing, Lin Li, Tao Liu   +11 more
wiley   +1 more source

Comment on: the Regulatory Role and Mechanism of TGFBI on tregs in the immune microenvironment of clear cell renal cell carcinoma

Zhonghua Zheng, Xiaorui Li, Jingsong Sun
openalex   +1 more source