Results 261 to 270 of about 337,050 (372)

Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinoma

Cancer Cell, 2021
L. Au, E. Hatipoglu, M. Robert de Massy, K. Litchfield, G. Beattie, A. Rowan, Desiree Schnidrig, R. Thompson, F. Byrne, S. Horswell, N. Fotiadis, S. Hazell, D. Nicol, S. Shepherd, A. Fendler, R. Mason, L. Del Rosario, K. Edmonds, K. Lingard, S. Sarker, Mary Mangwende, E. Carlyle, J. Attig, K. Joshi, I. Uddin, P. Becker, M. W. Sunderland, A. Akarca, I. Puccio, William W. Yang, T. Lund, Kim Dhillon, M. Vasquez, E. Ghorani, Hang Xu, Charlotte Spencer, J. López, A. Green, U. Mahadeva, E. Borg, M. Mitchison, D. Moore, I. Proctor, M. Falzon, L. Pickering, A. Furness, J. Reading, R. Salgado, T. Marafioti, M. Jamal-Hanjani, G. Kassiotis, B. Chain, J. Larkin, C. Swanton, S. Quezada, S. Turajlic, C. Abbosh, K. Shiu, J. Bridgewater, D. Hochhauser, Martin D. Forster, S. Lee, T. Ahmad, D. Papadatos-Pastos, S. Janes, P. Van Loo, Katey S. S. Enfield, N. Mcgranahan, A. Huebner, S. Beck, Peter J. Parker, H. Walczak, T. Enver, R. Hynds, Ron Sinclair, Chi-wah Lok, Zoe Rhodes, D. Moore, Reena Khiroya, G. Trevisan, P. Ellery, M. Linch, S. Brandner, C. Hiley, S. Veeriah, Maryam Razaq, H. Shaw, G. Attard, M. Akther, C. Naceur-Lombardelli, Lizi Manzano, M. Al-Bakir, S. Summan, N. Kanu, S. Ward, U. Asghar, E. Lim, F. Gishen, A. Tookman, P. Stone, C. Stirling, N. Hunter, Sarah Vaughan, L. Spain, Haixi Yan, B. Shum, N. Yousaf, S. Popat, O. Curtis, G. Stamp, A. Toncheva, E. Nye, Aida Murra, Justine Korteweg, D. Josephs, A. Chandra, J. Spicer, Ruby Stewart, Lara-Rose Iredale, T. Mackay, B. Deakin, D. Enting, S. Rudman, Sharmistha Ghosh, Lena Karapagniotou, E. Pintus, A. Tutt, S. Howlett, V. Michalarea, J. Brenton, C. Caldas, Rebecca Fitzgerald, M. Jimenez-Linan, E. Provenzano, A. Cluroe, G. Stewart, C. Watts, R. Gilbertson, U. McDermott, S. Tavaré, E. Beddowes, P. Roxburgh, A. Biankin, A. Chalmers, S. Fraser, K. Oien, A. Kidd, K. Blyth, M. Krebs, F. Blackhall, Y. Summers, C. Dive, R. Marais, F. Gomes, M. Carter, Joanne Dransfield, J. Le Quesne, D. Fennell, J. Shaw, B. Naidu, S. Baijal, B. Tanchel, G. Langman, Andrew Robinson, M. Collard, P. Cockcroft, C. Ferris, H. Bancroft, A. Kerr, G. Middleton, J. Webb, S. Kadiri, P. Colloby, B. Olisemeke, Rodelaine Wilson, I. Tomlinson, S. Jogai, C. Ottensmeier, David E. Harrison, M. Loda, A. Flanagan, M. McKenzie, A. Hackshaw, J. Ledermann, Kitty Chan, A. Sharp, L. Farrelly, Hayley Bridger, B. Challacombe, S. Chowdhury, W. Drake, A. Fernando, K. Harrison-Phipps, Peter Hill, C. Horsfield, T. O'brien, J. Olsburgh, A. Polson, M. Varia, H. Verma   +199 more
semanticscholar   +1 more source

EGFR‐TKIs Induced DPP4 Drives Metabolic Reprogramming of Persister Cells in Lung Cancer

Advanced Science, EarlyView.
Drug‐tolerant persister (DTP) cells emerge early during EGFR‐TKI treatment, preceding the development of acquired resistance. Elevated DPP4 in DTP cells drives metabolic reprogramming and antioxidant adaptation, promoting cell survival under drug pressure.
Yuanzhou Zhang, Xiaojun Zhang, Xupeng Yang, Xingshi Chen, Yuehong Wang, Jingying Hu, Rui Liu, Xiaoying Luo   +7 more
wiley   +1 more source

BMAL1 and ARNT enable circadian HIF2α responses in clear cell renal cell carcinoma. [PDF]

Nat Commun
Mello RM, Gomez Ceballos D, Sandate CR, Wang S, Jouffe C, Agudelo D, Uhlenhaut NH, Thomä NH, Simon MC, Lamia KA.   +9 more
europepmc   +1 more source

[Von-Hippel-Lindau gene mutation types. Association of gene expression signatures in clear cell renal cell carcinoma].

, 2008
Van Duc Luu, Bettina Fischer, Adriana von Teichman, Gunther Boysen, Kirsten D. Mertz, Philip Zimmermann, Holger Moch, Peter Schraml   +7 more
openalex   +1 more source

PLAUR+ Neutrophils Drive Anti‐PD‐1 Therapy Resistance in Patients with Hepatocellular Carcinoma by Shaping an Immunosuppressive Microenvironment

Advanced Science, EarlyView.
The present study reveals that PLAUR+ neutrophils are enriched in immunotherapy non‐responders and correlate with poor prognosis. PLAUR+ neutrophils dictate immunotherapy resistance in hepatocellular carcinoma by forming an immunosuppressive tumor microenvironment characterized by CD8+ T cell exclusion and macrophage‐dependent immune suppression.
Shaoqing Liu, Yanzhao Zhou, Gaoxiang Li, Bingwen Zhu, Fang Wu, Jinxue Zhou, Xiaobing Chen, Bo Qin, Yanxia Gao, Fazhan Wang, Yong Jiang, Wenxin Xu   +11 more
wiley   +1 more source

Integrated analysis of MIOX gene in prognosis of clear-cell renal cell carcinoma. [PDF]

Cell Death Dis
Wang Y, Lu J, Lin B, Chen J, Lin F, Zheng Q, Xue X, Wei Y, Chen S, Xu N.   +9 more
europepmc   +1 more source

Cancer Cell‐Derived Large Extracellular Vesicles Promote Venous Thromboembolism by Activating NETosis Through Delivering CYBA

Advanced Science, EarlyView.
Venous thromboembolism (VTE) is a major threat to cancer patients. Cancer‐derived large extracellular vesicles deliver CYBA (p22phox) to neutrophils, triggering reactive oxygen species (ROS) and citrullinated histone H3 (citH3) formation. This drives neutrophil extracellular traps formation (NETosis), elevating VTE risk.
Xiangji Li, Yingjiao Ju, Chenjie Xu, Shixiang Ma, Lan Sun, Qingdong Guo, Mingyuan Liu, Yibin Xie, Li Min   +8 more
wiley   +1 more source

Kinesin-related genes stratified the prognosis and immune responses of clear cell renal cell carcinoma. [PDF]

Eur J Med Res
Zang W, Ge L, Hu X, Xu T, Zhang Z, Zhang Y, Song F.   +6 more
europepmc   +1 more source

Faculty Opinions recommendation of HIF-alpha effects on c-Myc distinguish two subtypes of sporadic VHL-deficient clear cell renal carcinoma.

, 2008
Robert Abraham
openalex   +2 more sources

Combined classical cytogenetics and microarray‐based genomic copy number analysis reveal frequent 3;5 rearrangements in clear cell renal cell carcinoma [PDF]

, 2010
Jianming Pei, Madelyn Feder, Tahseen Al‐Saleem, Zemin Liu, Angen Liu, Gary R. Hudes, Robert G. Uzzo, Joseph R. Testa   +7 more
openalex   +1 more source