Results 361 to 370 of about 337,050 (372)

Biomarkers in clear cell renal cell carcinoma

Expert Review of Anticancer Therapy, 2007
The treatment of advanced renal cell carcinoma (RCC) has evolved significantly following the identification of the von Hippel-Lindau (VHL) gene and the function of its protein, and subsequent development of antiangiogenic therapies. A series of clinical trials resulted in the approval of three new agents with significant activity in this disease ...
Saby George, Ronald M. Bukowski
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Misdiagnosis of clear cell renal cell carcinoma

Nature Reviews Urology, 2011
Clear cell renal cell carcinoma (RCC) represents the most common histological subtype of malignant kidney tumors. Based on symptoms alone, clear cell RCC is indistinguishable from other histological classes of RCC unless the tumor is present in the context of an RCC syndrome. Histopathological examination is, therefore, important to accurately identify
Vladimir Valera, Maria J. Merino
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The cross‐talk between Abl2 tyrosine kinase and TGFβ1 signalling modulates the invasion of clear cell Renal Cell Carcinoma cells

FEBS Letters, 2022
Clear cell Renal Cell Carcinoma (ccRCC) is the most common and metastatic urological cancer. Molecular players of ccRCC progression and metastasis are not completely known.
S. De Marco, B. Torsello, E. Minutiello, I. Morabito, C. Grasselli, S. Bombelli, N. Zucchini, G. Lucarelli, G. Strada, R. Perego, C. Bianchi   +10 more
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Cell heterogeneity in clear cell renal cell carcinoma

APMIS, 2013
The aim of this study was to define the histological spectrum, frequency and significance of nonconventional tumour cells in clear cell renal cell carcinomas (CCRCC). Fifty‐one totally sampled CCRCC were studied histologically to evaluate the spectrum of cell morphology variability, its frequency and significance, and their correlation with tumour ...
José I. López, Gorka Larrinaga, Rosa Guarch, Alexandra Corominas-Cishek, Roberto Orozco   +4 more
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T2 CLEAR CELL RENAL CELL CARCINOMA IS A RARE ENTITY: A STUDY OF 120 CLEAR CELL RENAL CELL CARCINOMAS

Journal of Urology, 2005
In 2002 the American Joint Committee on Cancer revised the TNM staging system, introducing subclassification for T1 tumors, and invasion of renal sinus fat and sinus veins in categories T3a and T3b, respectively. Since renal sinus invasion represents the most common site of extrarenal extension, the relationship between size, and renal sinus invasion ...
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MYC pathway is activated in clear cell renal cell carcinoma and essential for proliferation of clear cell renal cell carcinoma cells

Cancer Letters, 2009
Clear cell renal cell carcinoma (ccRCC) is the major and aggressive subtype of RCC. Previously, we identified 383 differentially expressed genes by analyzing full-length cDNA libraries of ccRCC and normal kidney tissues. In this study, we applied functional network analysis to the differentially expressed genes for identifying deregulated molecular ...
Wei-Chou Lin, Yu-Chi Chen, Yih-Ching Su, Chyong-Ing Hsu, Jung-Yaw Lin, Wen-Hsin Chang, Pei-Tzu Wu, Sai-Wen Tang, Ming-Kuen Lai, Yen-Han Lai   +9 more
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Chemotherapy for Non–Clear-Cell Renal Cell Carcinoma

Clinical Genitourinary Cancer, 2006
Clear-cell carcinoma is the most common histopathologic subtype of kidney tumors. Consequently, clinical trials for advanced-stage kidney cancer have focused on patients with clear-cell carcinoma and not on the less common subtypes, including papillary, chromophobe, collecting-duct carcinoma, and sarcomatoid-variant tumors.
Matthew I. Milowsky, David M. Nanus, Kevin A. David   +2 more
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Clear cell papillary renal cell carcinoma

Pathology, 2014
Clear cell papillary renal cell carcinoma is a newly described variant of renal cell carcinoma (RCC). The International Society of Urological Pathology (ISUP) Vancouver Classification of Renal Neoplasia has recently endorsed it as a distinct epithelial tumor entity and recommended the inclusion of this tumor in the ISUP Vancouver modification of the ...
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Cytomorphology of clear cell papillary renal cell carcinoma

Cancer Cytopathology, 2016
BACKGROUNDClear cell papillary renal cell carcinoma (CCPRCC) shares some morphologic and immunohistochemical markers with clear cell RCC and papillary RCC. To the author's knowledge, its cytomorphology on fine‐needle aspiration (FNA) or touch preparations (TPs) of core needle biopsy specimens has not been well delineated in the English language ...
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Pure Erythropoiesis in Clear Cell Renal Cell Carcinoma

International Journal of Surgical Pathology, 2010
Extramedullary hematopoiesis (EMH) is a phenomenon in which benign immature hematopoietic cells are found in sites other than the bone marrow. Although usually associated with an underlying hematologic abnormality such as myelofibrosis, it can be found in some physiologic states or occasionally within solid tumors.
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