Results 231 to 240 of about 1,025,454 (297)

Seizure due to Lamotrigine Underexposure During High-Volume CRRT for Hyperammonaemia: A Case Report. [PDF]

Case Rep Crit Care
van Herwerden MC, Elderman JH, Favie LMA, Wagenmakers M.   +3 more
europepmc   +1 more source

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

FEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks, Garth L. Maker, Emily C. Davies, Berin A. Boughton, Samantha Lodge   +4 more
wiley   +1 more source

Chronic kidney disease and cognitive decline: choroid plexus remodeling, glymphatic dysfunction, and alzheimer biomarker interpretation. [PDF]

Neurol Sci
Corrêa LMA, Oliveira da Silva R, Brandão LKV, Delmiro Silva YR, da Silva ÉVB, Tretow J, Gomes EDC, Fernandes CCS, Moreira GNCM, Zanella J.   +9 more
europepmc   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Physiologically Based Pharmacokinetic Modeling to Assess Transporter-Mediated Drug-Drug Interactions in Support of Labeling Recommendations for Zavegepant Nasal Spray. [PDF]

Clin Pharmacol Ther
Ke A, Callegari E, Varma MVS, Ladumor MK, Muto C, Bertz RJ, Jones HM, Sahasrabudhe V, Liu J.   +8 more
europepmc   +1 more source

CLEARANCE: Apple MacBook-Air $36.90, Expires 10.31.2015

, 2015
Beats Black Friday Clearance
core  

Population pharmacokinetic analysis of pirtobrutinib, a non-covalent BTK inhibitor, in patients with hematological malignancies from the Phase 1/2 BRUIN study. [PDF]

Cancer Chemother Pharmacol
Bell R, O'Brien LM, Yuen E, Liu D, Chapman SC.   +4 more
europepmc   +1 more source

The Hippo signalling pathway regulates the timing of epithelial cell replacement during Drosophila abdominal morphogenesis. [PDF]

J Cell Sci
Lyon K, Manning SA, Burke R.
europepmc   +1 more source

Erratum: Drug Clearance and Dosing During CytoSorb Hemoadsorption: A Systematic Review: Erratum. [PDF]

Crit Care Explor
Klaus T, Honoré PM, Bottari G, De Rosa S, Kindgen-Milles D, Schneider A, Marczin N, Adamson H, Scheier J, Deliargyris EN, Nolin TD.   +10 more
europepmc   +1 more source