Results 71 to 80 of about 497,558 (281)
CD24 signalling through macrophage Siglec-10 is a target for cancer immunotherapy. [PDF]
Ovarian cancer and triple-negative breast cancer are among the most lethal diseases affecting women, with few targeted therapies and high rates of metastasis. Cancer cells are capable of evading clearance by macrophages through the overexpression of anti-
Barkal, Amira A +10 more
core
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
High voltage direct current (HVDC) transmission is being widely implemented for long-distance electrical power transmission due to its specific benefits over high voltage alternating current (HVAC) transmission.
Kumail Hassan Kharal +6 more
doaj +1 more source
Annular Seals of High Energy Centrifugal Pumps: Presentation of Full Scale Measurement [PDF]
Prediction of rotordynamic behavior for high energy concentration centrifugal pumps is a challenging task which still imposes considerable difficulties. While the mechanical modeling of the rotor is solved most satisfactorily by finite element techniques,
Florjancic, S. +2 more
core +1 more source
Intake Ground Vortex Prediction Methods [PDF]
For an aircraft turbofan engine in ground operations or during the take-off run a ground vortex can occur which is ingested and could potentially adversely affect the engine performance and operation.
MacManus, David G., Murphy, J. P.
core +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Clearance of materials from accelerator facilities
A new Technical Standard that supports the clearance of materials and equipment (personal property) from U.S. Department of Energy (DOE) accelerator facilities has been developed.
Rokni Sayed H. +6 more
doaj +1 more source
Creatinine clearance in selection of living kidney donor among the Malaysian population: is it safe?
Background Assessment of donor renal function is made by the measurement of Glomerular Filtration Rate (GFR). Exogenous markers are preferred over creatinine clearance and are widely used for measuring GFR.
Chee Keong Thye +4 more
doaj +1 more source
Enhancing quantum entropy in vacuum-based quantum random number generator
Information-theoretically provable unique true random numbers, which cannot be correlated or controlled by an attacker, can be generated based on quantum measurement of vacuum state and universal-hashing randomness extraction.
Cheng, Chen +5 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source

