Results 41 to 50 of about 789,108 (324)
A versatile depigmentation, clearing, and labeling method for exploring nervous system diversity
Science Advances, 2020 A tailored protocol combines pigment removal with clearing, facilitating labeling and whole-body imaging across phylogeny. Tissue clearing combined with deep imaging has emerged as a powerful alternative to classical histological techniques.
M. Pende +15 more
semanticscholar +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Effects of endocrine-disrupting chemical exposure on zebrafish ovarian follicles [PDF]
, 2017 The process of oocyte maturation involves both nuclear and cytoplasmic events that are essential for the production of viable eggs and subsequent fertilization in sexually reproducing animals.
D\u27Angelo, Josephine +1 more
core +2 more sources
Murmurations: Journal of Transformative Systemic Practice, 2023 Some context I brought these words together in 2022 following a weekend I spent with my younger sister, Annemarie, and my younger brother, James, who came to visit me together, something that hadn’t happened before and I was left humbled by their visit.
openaire +2 more sources
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
In-vivo and ex-vivo optical clearing methods for biological tissues: review.
Biomedical Optics Express, 2019 Every optical imaging technique is limited in its penetration depth by scattering occurring in biological tissues. Possible solutions to overcome this problem consist of limiting the detrimental effects of scattering by reducing optical inhomogeneities ...
I. Costantini +4 more
semanticscholar +1 more source
Routine Optical Clearing of 3D-Cell Cultures: Simplicity Forward
Frontiers in Molecular Biosciences, 2020 Three-dimensional cell cultures, such as spheroids and organoids, serve as increasingly important models in fundamental and applied research and start to be used for drug screening purposes.
Elina Nürnberg +14 more
semanticscholar +1 more source
FEBS Letters, EarlyView.Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke +2 more
wiley +1 more source
A stepwise emergence of evolution in the RNA world
FEBS Letters, EarlyView.How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
3D histopathology of human tumours by fast clearing and ultramicroscopy
Scientific Reports, 2020 Here, we describe a novel approach that allows pathologists to three-dimensionally analyse malignant tissues, including the tumour-host tissue interface.
Inna Sabdyusheva Litschauer +13 more
semanticscholar +1 more source