Results 41 to 50 of about 1,732 (146)

The role of crystallographic orientation of martensitic variants on cleavage crack propagation [PDF]

open access: yesarXiv, 2016
Cleavage crack propagation has been investigated in a low-carbon lath-martensitic steel using electron back-scattered diffraction technique. The ability of different martensitic boundaries within prior-austenite grain, such as sub-block, block and packet boundaries to resist cleavage crack propagation has been estimated in terms of Kurdjumov-Sachs ...
arxiv  

Social progress at the expense of economic equality? New data on left parties' equality preferences

open access: yesEuropean Journal of Political Research, EarlyView.
Abstract Have concerns about equal rights and equal chances crowded out economic equality as a priority of left parties? Despite the increased importance of inequality in political science, this contentiously fought debate has been standing on shaky empirical foundations.
ALEXANDER HORN   +2 more
wiley   +1 more source

Reverse Engineering of Proteasomal Translocation Rates [PDF]

open access: yesarXiv, 2008
We address the problem of proteasomal protein translocation and introduce a new stochastic model of the proteasomal digestion (cleavage) of proteins. In this model we account for the protein translocation and the positioning of cleavage sites of a proteasome from first principles.
arxiv  

Computational Synthesis of Substrates by Crystal Cleavage [PDF]

open access: yesarXiv, 2020
The discovery of novel substrate materials has been dominated by trial and error, opening the opportunity for a systematic search. To identify stable crystal surfaces, we generate bonding networks for materials from the Materials Project database with one to five atoms in the primitive unit cell.
arxiv  

VDAC1‐Targeted NHK1 Peptide Recovers Mitochondrial Dysfunction Counteracting Amyloid‐β Oligomers Toxicity in Alzheimer's Disease

open access: yesAging Cell, EarlyView.
Amyloid‐β (Aβ) oligomers affect VDAC1 electrophysiology and the physiological metabolic cross‐talk between cytosol and mitochondria. The use of a small, synthetic VDAC1‐antagonist peptide, derived from hexokinase, restores mitochondrial functionality, and respiration in cellular models of Alzheimer's disease. ABSTRACT Mitochondrial dysfunction has been
Fabrizio Cavallaro   +10 more
wiley   +1 more source

An atomistic-to-continuum analysis of crystal cleavage in a two-dimensional model problem [PDF]

open access: yesarXiv, 2011
A two-dimensional atomic mass spring system is investigated for critical fracture loads and its crack path geometry. We rigorously prove that, in the discrete-to-continuum limit, the minimal energy of a crystal under uniaxial tension leads to a universal cleavage law and energy minimizers are either homogeneous elastic deformations or configurations ...
arxiv  

From Cosmic Explosions to Terrestrial Fires?: A Reply [PDF]

open access: yesarXiv, 2020
Deschamps and Mottez (hereafter DM) argue that the Gauss-Matuyama terrestrial magnetic field reversal may have left a vanishing main dipole moment to the field for a time of order 10,000 years. They say this may have allowed an enhanced cosmic ray flux, boosting the effect we proposed in Melott and Thomas (2019).
arxiv  

Geology of symmetric grounds [PDF]

open access: yesarXiv, 2019
Let us say that a model of $\mathsf{ZF}$ is a symmetric ground if $V$ is a symmetric extension of the model. In this paper, we investigate set-theoretic geology of symmetric grounds. Under a certain assumption, we show that all symmetric grounds of $V$ are uniformly definable. We also show that if $\mathsf{AC}$ is forceable over $V$, then the symmetric
arxiv  

Can pseudocomplementary peptide nucleic acid nucleases (pcPNANs) be a new tool for genetic engineering? [PDF]

open access: yesarXiv, 2014
Zinc-finger nucleases (ZFNs) and transcription activator-like effector nucleases (TALENs) comprise a powerful class of tools that are redefining the boundaries of biological research. Although these technologies have begun to enable targeted genome modifications, there remains a need for new technologies that are affordable, scalable, and easy to ...
arxiv  

Martini coarse-grained model for clay-polymer nanocomposites [PDF]

open access: yesarXiv, 2019
We have developed a coarse-grained (CG) model of a polymer-clay system consisting of organically modified montmorillonite nanoclay as the nanoparticle in accordance with the MARTINI forcefield. We have used mechanical properties and cleavage free energy of clay particle to respectively parameterize bonded and nonbonded interaction parameters for an ...
arxiv  

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