Results 41 to 50 of about 137,600 (267)

The Bondei object pronoun in clefts and pseudo-clefts.pdf

Studies in African Linguistics, 1988
Verbs in Bondei, a Bantu language spoken in East Africa, have crossreferencing pronouns which agree in noun class with the subject and object of the clause.
Elizabeth G. Weber
doaj  

Family based and case–control designs reveal an association of TFAP2A in nonsyndromic cleft lip only among Vietnamese population

Molecular Genetics & Genomic Medicine, 2021
Aims Dozens of causative genes and their mechanisms of nonsyndromic cleft lip with or without cleft palate (NSCL/P) were revealed through genome‐wide association and linkage studies.
Duc Minh Nguyen, Satoshi Suzuki, Hideto Imura, Teruyuki Niimi, Hiroo Furukawa, Thanh‐Van Ta, Son Minh Tong, Tra Thu Nguyen, Loc Nguyen Gia Pham, Duy Le Tran, Nagato Natsume   +10 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Association of Perioperative Antibiotics with the Prevention of Postoperative Fistula after Cleft Palate Repair

Plastic and Reconstructive Surgery, Global Open
Background:. There is debate amongst surgeons regarding the use of antibiotics to prevent fistulae after palatoplasty. Prescribing should be evidence based, as antibiotic stewardship is integral to reducing antibiotic resistance. Our aim was to determine
Alex Davies, MBChB, FRCS(Plast), Amy Davies, MSc, Barry Main, PhD, MFDS, FRCS(OMFS), Yvonne Wren, MEd, PhD, CertMRCSLT, Scott Deacon, MOrth, MDTFEd, FDS(Orth), Alistair Cobb, FRCS(OMFS), FDSRCS(Eng), MFSEM(UK), Neil McLean, BSc, MD, FRCS, David David, AC, MD, FRACS, Shaheel Chummun, MBBS, MASurg(Cranio), FRCS(Plast)   +8 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Thebesian Veins Draining to the Left Ventricle, Mimicking Left Ventricular Noncompaction

JACC: Case Reports, 2020
Left ventricular noncompaction cardiomyopathy (LVNC) was diagnosed in a 59-year-old woman, based on echocardiography. Later, diagnostic criteria were also found positive by cardiac magnetic resonance (CMR).
Simon F. Stämpfli, MD, MSc, Bart W. De Boeck, MD, PhD, Florim Cuculi, MD, Richard Kobza, MD   +3 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Palatal pain due to exostosis of the posterior palatal spine in a cleft patient

Journal of Cleft Lip Palate and Craniofacial Anomalies, 2014
Facial pain is a complex disorder to diagnose and to manage. Problems in the craniofacial area may present with conflicting and blurred symptomatology that may result in an obscured clinical picture where a single etiological factor may seem unlikely ...
Sharan Naidoo, Gieljam J Roode, Kurt-W Bütow   +2 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source