Results 41 to 50 of about 193,265 (306)

Comparison of Corresponding Scores From the Cleft Hearing Appearance and Speech Questionnaire (CHASQ) and CLEFT-Q in Swedish Patients With Cleft Lip and/or Palate

, 2020
Objective: The primary aim of this study was to compare corresponding scores between 2 existing cleft-specific patient-reported outcome measures (PROMs)—Cleft Hearing Appearance and Speech Questionnaire (CHASQ) and CLEFT-Q.
Stiernman, Mia,, Klintö, Kristina, Kristianstad University., Becker, Magnus, Persson, Martin,, Stiernman, Mia, Persson, Martin, Klintö, Kristina,, Lund University., Becker, Magnus,   +9 more
core   +1 more source

Characterization of Cytokines and Proliferation Marker Ki67 in Cleft Affected Lip Tissue

Medicina, 2019
Background and objectives: Cleft lip palate takes the second place among all anomalies. The complex appearance of cytokines and proliferation markers has still not been clarified despite their possible crucial role in cleft tissue.
Mara Pilmane, Elga Sidhoma, Ilze Akota, Dzintra Kazoka   +3 more
doaj   +1 more source

Oral health related quality of life changes in standard cleft and surgery patients- A clinical study

Journal of Pharmacy and Bioallied Sciences, 2021
Background: Malocclusions are expected to affect subjective attraction, social recognition, and intellect. For dentofacial deformities, functional concerns can also arise. The previous research has established a gradient on oral health-related quality of
Jaideep Singh, Amit Kumar, Vasudha Sodani, Amit Kumar, Moazzam Jawaid, Milind Wasnik   +5 more
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Early Dimensional Changes in Maxillary Cleft Size and Arch Dimensions of Children with Cleft Lip and Palate and Cleft Palate

, 2013
Objective To study early changes in cleft size and maxillary arch dimensions and to evaluate these changes in relation to performed surgical procedures. Design Retrospective longitudinal study.
Reiser, Erika,, Erika Reiser, Skoog, Valdemar,, Anna Andlin-Sobocki, Valdemar Skoog, Andlin-Sobocki, Anna,   +5 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

The FGF and FGFR gene family and risk of cleft lip with or without cleft palate [PDF]

, 2013
Background : Isolated, nonsyndromic cleft lip with or without cleft palate is a common human congenital malformation with a complex and heterogeneous etiology.
지선하
core   +1 more source

Surgical management of congenital bifid tongue with associated cleft palate, tongue and palatal hamartoma: A rare case report

JPRAS Open
Congenital bifid tongue is a rare developmental anomaly, typically associated with other oral malformations such as cleft palate and lingual hamartomas.
Ali Adil, Bilal Mahmood Bhandari, Ayisha Ayub   +2 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source