Results 31 to 40 of about 251 (197)

Treatment of Cleft Foot Deformity using Fish Mouth Incision and Suture-Button in Paediatric Foot

Sultan Qaboos University Medical Journal, 2022
القدم المشقوقة هي شذوذ خلقي يتميز بغياب عظام المشط والسلامات. يشاهد عادة في الأطفال الذين يعانون من خلل التنسج خارج الأصابع ومتلازمة الشقوق (EEC) التي تتراوح من الشق المتوسط حتى منتصف مشط القدم إلى الشق العميق حتى عظام الرصغ. تمت تجربة العلاج الجراحي في شكل إغلاق مشقوق، واستئصال عظم مشط القدم البدائي وتثبيت عظام مشط القدم عبر السلك K لإدارة مثل هذه ...
Amit Narang, Ayanjit Chattopadhyay, Amit Kumar Sharma, Sumit Gupta   +3 more
openaire   +4 more sources

New Surgical Technique for Cleft Hand and Foot Using a Lateral Pantaloon Flap

Plastic and Reconstructive Surgery, Global Open
Summary:. Various surgical techniques for cleft hand closure have been reported. Cleft closure aims to improve cosmetic appearance, and the form of interdigital spaces should be drawn closer to normal.
Chizuru Umeda, MD, PhD, Koichi Ueda, MD, PhD, Kurumi Fujiwara, MD, Hiromi Kino, MD, PhD, Yuri Yae, MD   +4 more
doaj   +1 more source

Split-hand/feet malformation: A rare syndrome

Journal of Family Medicine and Primary Care, 2016
Split-hand/split-foot malformation (SHFM) is mainly inherited as an autosomal dominant trait with incomplete penetrance and characterized by malformation of the limb involving the central rays of the autopod.
Bahubali D Gane, P Natarajan
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Anencephaly and its Associated Malformations [PDF]

Journal of Clinical and Diagnostic Research, 2014
Introduction: Anencephaly is a serious neural tube defect in which parts of the brain and skull are not developed. But apart from this it is also associated with other malformations which are not related to neural tube in development.
Ravikiran Ashok Gole, Pritee Madan Meshram, Shanta Sunil Hattangdi   +2 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The prevalence of foot-and-mouth disease in Asia

Frontiers in Veterinary Science, 2023
Foot-and-mouth disease (FMD) is listed among the highly contagious diseases in animals and is endemic throughout the Asian continent. The disease is caused by the Foot-and-mouth disease virus (FMDV) and affects a wide variety of domesticated animals as ...
Munazza Aslam, Khalid A. Alkheraije
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source