Speech and expressive language in Swedish-speaking children with unilateral cleft lip and palate [PDF]
, 2014 Introduction and aims: A cleft palate may hamper development of speech and expressive language. Expressive language, including phonology, has been sparsely explored in children with cleft lip and palate, and extended knowledge is essential in order to ...
Klintö, Kristina
core +1 more source
Advanced Science, EarlyView.Employing snRNA‐seq post‐MCAO‐induced retinal ischemia (RI), this study revealed a novel Hmga2‐high Müller cell subpopulation. Hmga2 knockout alleviated neuroinflammation and RI symptoms, potentially by binding PI3K and regulating Müller cell autophagy.
Weihao Lv +11 more
wiley +1 more source
Evaluation of unilateral cleft lip repairs and the evolution of a new technique based on experience and research [PDF]
, 2011 MSc, Plastic and Reconstructive Surgery, Faculty of Health Sciences, University of the WitwatersrandEvolution of cleft lip repair has been ongoing for many years.
Christofides, Efthimios Andreas
core
RelA Inhibits Embryonic Myogenesis by Coordinately Regulating a Novel Distal Enhancer of Myogenin
Advanced Science, EarlyView.Maternal obesity (MO) accounts for more than 40% of pregnancies in the United States, induces inflammation, and impairs embryonic myogenesis, known to program muscle dysfunction in offspring. Inflammation enhances the binding of RelA to a novel distal enhancer located 4 kb upstream of myogenin promoter to inhibit embryonic myogenesis, which is ...
Md Nazmul Hossain +9 more
wiley +1 more source
Local expression of inflammatory cytokines in the facial tissue of children with a cleft lip and palate [PDF]
, 2012 The cleft lip and/or palate are among the most common congenital anomalies that occur in early development. Cytokines play an important role in the proliferation, growth, differentiation, survival and the functional activity of many cells and the ...
Akota, Ilze, Pilmane, Mara, Smane, Liene
core +3 more sources
PLoS ONE, 2016 Background Although conventional two-dimensional (2D) methods for orthognathic surgery planning are still popular, the use of three-dimensional (3D) simulation is steadily increasing.
Daniel Lonic +5 more
semanticscholar +1 more source
HIFU‐Driven Targeted Pyroptosis Therapy in Basal‐Like Breast Cancer
Advanced Science, EarlyView.This study presents a HIFU‐driven pyroptosis strategy for BLBC treatment. Combining HIFU with platelet‐membrane hybridized liposomes encapsulating mitoxantrone enhances tumor targeting and efficacy. The synergistic treatment modulates key epigenetic regulators and activates the pyroptotic pathway through ROS generation and inflammasome signaling ...
Xiaomin Su +13 more
wiley +1 more source
Facial Soft-Tissue Asymmetry in 3D Cone Beam Computed Tomography Images of Children with Surgically Corrected Unilateral Clefts [PDF]
, 2014 Cleft lip with or without cleft palate (CL/P) is a relatively common craniofacial malformation involving bony and soft-tissue disruptions of the nasolabial and dentoalveolar regions.
Ghoneima, Ahmed +2 more
core
Novel GREM1 Variations in Sub-Saharan African Patients With Cleft Lip and/or Cleft Palate [PDF]
, 2018 Objective: Cleft lip and/or cleft palate (CL/P) are congenital anomalies of the face and have multifactorial etiology, with both environmental and genetic risk factors playing crucial roles.
Abdur-Rahman, Lukman O. +23 more
core +2 more sources
KRAS/ABHD17C/ALOX15B Axis Promotes Pancreatic Cancer Progression via Ferroptosis Evasion
Advanced Science, EarlyView.Phosphorylation of ABHD17C induced by KRASmut/ERK signaling facilitates ALOX15B depalmitoylation and degradation via the CUL4/DDB1/DCAF10 complex, thereby enabling KRASmut‐PDAC cell to evade ferroptosis. Methyl protodioscin inhibits KRASmut‐PDAC progression by disrupting the ABHD17C/ALOX15B interaction and inducing ferroptosis, which represents a ...
Man Li +12 more
wiley +1 more source