Results 51 to 60 of about 50,330 (260)

Integrated Transcriptomics Reveals Evolutionary Trajectories and Cell Density‐Dependent Mechanisms in Aldosterone‐Producing Adenomas

Advanced Science, EarlyView.
Aldosterone‐producing adenomas (APAs) develop via two distinct paths: directly from adrenal zona glomerulosa (zG) cells, or stepwise from zG cells through aldosterone‐producing micronodules (APMs) before progressing to APAs. Advanced single‐cell and spatial analyses identified distinct cell states linked to oxidative stress and cell–cell interactions ...
Zhuolun Sun, Changying Jing, Martina Tetti, Siyuan Gong, Jia Wei, Yingxian Pang, Martin Reincke, Tracy Ann Williams   +7 more
wiley   +1 more source

Post-surgical dentofacial deformities and dental treatment needs in cleft-lip-palate children: A clinical study

Journal of Indian Society of Pedodontics and Preventive Dentistry, 2011
Background: Cleft lip and palate is a common congenital defect. It is one of the most common facial deformities occurring in major racial and ethnic groups.
V Krishna Priya, J Sharada Reddy, Y Ramakrishna, C Pujita Reddy   +3 more
doaj   +1 more source

The Use of Eye-tracking Technology in Cleft Lip: A Literature Review

Plastic and Reconstructive Surgery, Global Open, 2023
Background:. Eye-tracking has become an increasingly popular research tool within the field of cleft lip and/or palate (CL+/−P). Despite this, there are no standardized protocols for conducting research.
Alexander T. Plonkowski, R. William F. Breakey, MRCS, PhD, BSc, Jenny C. A. Read, BA, MSc, DPhil, David C. G. Sainsbury, MBBS, MSc, FRCS(Plast)   +3 more
doaj   +1 more source

Aesthetic satisfaction in lip and palate clefts: a comparative study between secondary and tertiary bone grafting [PDF]

, 2018
Lip and palate cleft represent one of the most frequently occurring congenital deformity, which includes dental anomalies, such as variation in tooth number and position.
Brauner, E, De Angelis, F, Di Carlo, S, Jamshir, S, Mezi, S, Pompa, G, Quarato, A, Tiroli, R C   +7 more
core   +1 more source

Maternal Preconception Antibiotic Exposure Disrupts Microbial Succession: A Transgenerational Risk for Offspring Gut Mucosal Immaturity and Colitis Susceptibility

Advanced Science, EarlyView.
This study reveals that maternal antibiotic exposure prior to conception disrupts intergenerational gut microbial succession. By enhancing maternal‐offspring microbial transmission, altering microbial developmental trajectories and increasing selective pressures during community assembly, these disturbances lead to persistent gut mucosal immaturity and
Yuzhu Chen, Ruqiao Duan, Cunzheng Zhang, Gaonan Li, XiaoLin Ji, Qi Zhang, Fei Pei, Kun Wang, Liping Duan   +8 more
wiley   +1 more source

A Novel Voxel-based Technique for 3-Dimensional Transparent Visualization of Lip–Nasal Vasculature

Plastic and Reconstructive Surgery, Global Open
Summary:. Conventional imaging cannot capture the spatial relationship between soft tissue and vasculature in patients with cleft lip. Here, a novel technique integrating micro–computed tomography imaging with voxel-based 3-dimensional reconstruction was
Hongru Zhou, MD, Yu Yao, MD, Congxiao Zhu, MD, Leheng Jiang, MD, Yilue Zheng, MD, Hengyuan Ma, MD, Liya Jiang, MD, Ningbei Yin, MD   +7 more
doaj   +1 more source

The registry of congenital cleft lip and cleft palate in Iran: Three-years pilot results and learned lessons

Journal of Craniomaxillofacial Research, 2022
Background: Cleft lip and cleft palate are the most common maxillofacial congenital defects leading to facial deformity and complications in nutrition, respiration, and social interaction.
Abbas Habibelahi, Naghmeh Bahrami, Farnoush Mohammadi, Sarvin Sarmadi, Mohammad Hosein Amirzade Iranaq, Masoume Farhangiyan, Mohammad Bayat   +6 more
doaj  

Retrospective longitudinal analysis of phonetic and phonological cleft palate speech characteristics [PDF]

, 2015
In this study, we analysed phonetic and phonological consonant characteristics of cleft palate speech (CPS) at ages 5 and 10 in cleft palate with/without cleft lip (CP±CL) based on Cleft Audit Protocol for Speech – Augmented (CAPS-A) data collected in ...
Cohen, Wendy, Crampin, Lisa, Lowit, Anja, Schulz, Erika   +3 more
core  

Accumulation of rare coding variants in genes implicated in risk of human cleft lip with or without cleft palate. [PDF]

, 2019
Cleft lip with/without cleft palate (CLP) is a common craniofacial malformation with complex etiologies, reflecting both genetic and environmental factors. Most of the suspected genetic risk for CLP has yet to be identified. To further classify risk loci
Asrani, Kripa, Marini, Nicholas J, Rine, Jasper, Shaw, Gary M, Yang, Wei   +4 more
core   +2 more sources

PAF Triggered Pyroptotic NETosis Aggravates Myocardial Ischemia/Reperfusion Injury

Advanced Science, EarlyView.
Platelet activating factor (PAF) secreted by cardiomyocytes during MI/R, drives NETs formation and subsequent NETosis. PAF/NETosis signaling activation is an initiative and causal factor in driving MI/R injury. This study identifies dapagliflozin as a potent NETosis inhibitor, and demonstrates that manipulating PAF‐NETosis signal by dapagliflozin or ...
Jiawei Wu, Shule Zhang, Ruofan Du, Lina Kang, Guodong Zhao, Xue Bao, Haochi Yang, Ziqing Xie, Tianyu He, Huiyong Sun, Haiping Hao, Lijuan Cao   +11 more
wiley   +1 more source