Results 81 to 90 of about 94,979 (341)

Targeting Itga8 Mitigates Neurogenic Bladder Fibrosis Driven by Trem2⁺ Macrophage‐Derived Fn1 via FAK/RhoA/ROCK Signaling

Advanced Science, EarlyView.
Normal bladders exhibit quiescent fibroblasts/macrophages, whereas neurogenic bladders show acute‐phase Itga8⁺ fibroblast expansion driven by Trem2⁺ macrophage‐secreted Fn1, which activates FAK/RhoA/ROCK signaling, promotes cytoskeletal remodeling, and upregulates pro‐fibrotic genes.
Jiaxin Wang, Siyuan Wang, Lida Ren, Xinqi Liu, Lei Zhang, Peng Hu, Wenchao Xu, Shuaixiang Zheng, Jihong Liu, Qing Ling   +9 more
wiley   +1 more source

Facial Soft-Tissue Asymmetry in 3D Cone Beam Computed Tomography Images of Children with Surgically Corrected Unilateral Clefts [PDF]

, 2014
Cleft lip with or without cleft palate (CL/P) is a relatively common craniofacial malformation involving bony and soft-tissue disruptions of the nasolabial and dentoalveolar regions.
Ghoneima, Ahmed, Kula, Katherine, Starbuck, John M   +2 more
core  

Novel GREM1 Variations in Sub-Saharan African Patients With Cleft Lip and/or Cleft Palate [PDF]

, 2018
Objective: Cleft lip and/or cleft palate (CL/P) are congenital anomalies of the face and have multifactorial etiology, with both environmental and genetic risk factors playing crucial roles.
Abdur-Rahman, Lukman O., Adeyemo, A. A., Adeyemo, Wasiu Lanre, Agbenorku, Pius, Aregbesola, Babatunde S., Audu, Rosemary, Bello, Seidu A., Busch, Tamara D., Butali, Azeez, Donkor, Peter, Eshete, Mekonen A., Gowans, Lord Jephthah Joojo, Marazita, Mary L., Mossey, Peter A., Murray, Jeffrey C., Obiri-Yeboah, Solomon, Oginni, Fadekemi, Ogunlewe, Mobolanle O., Olaitan, Peter B., Onwuamah, Chika, Oseni, Ganiyu, Oti, Alexander A., Owais, Arwa, Plange-Rhule, Gyikua   +23 more
core   +3 more sources

Correlative Imaging Platform Linking Taste Cell Function to Molecular Identity

Advanced Science, EarlyView.
A correlative imaging platform is developed to study how individual taste cells respond to different taste qualities. By linking cellular activity with molecular identity and environmental context, dual‐tuned taste cells capable of detecting both sweet and umami stimuli are identified.
Sungho Lee, Minjae Kim, Gha Yeon Park, Jubeen Yoon, Kunyoo Shin, Chang Ho Sohn, Myunghwan Choi   +6 more
wiley   +1 more source

ALDOA‐Mediated Metabolic Reprogramming is a Targetable Vulnerability for Ferroptosis Sensitization in Cancer

Advanced Science, EarlyView.
ALDOA‐depletion‐mediated glycolytic reprogramming promotes autophagy‐mediated degradation of MBOAT2, increasing the ratio of phospholipids containing pro‐ferroptotic polyunsaturated fatty acids over anti‐ferroptotic monounsaturated fatty acids, and thus sensitizing cancer cells to ferroptosis.
Pengqi Wang, Kezhang He, Bowen Wang, Wei Zhou, Ying Zhang, Tianhua Ma, Sheng Ding   +6 more
wiley   +1 more source

Tessier number 30 clefts with congenital heart defects [PDF]

, 2015
Introduction: Midline cleft of mandible, classified as Tessier 30 clefts is extremely rare, with less than 100 reported cases in the latest studies. Variations in severity and associated malformations have been reported before. Case Presentation: In this
Aminolsharieh Najaf, S., Hasheminejad, R., Mirfazeli, A., Shafee, A., Tafreshi, M.   +4 more
core   +1 more source

Exclusive Se‐O Coordination and Fe‐doping Complementation: A Catalytic Strategy for Enhanced Sulfur Redox in Li‐S Batteries

Advanced Science, EarlyView.
Exclusive Se‐O coordination and Fe‐doping complementation significantly improve conductivity and modulate the d‐band centers, which strongly anchor polysulfides in bidirectional catalysis and reduce the energy barriers for the Li2S nucleation and dissociation, achieving high‐apacity retention, exceptional rate capability, and stable cycling capability.
Zhao Yang, Yu Wang, Jingchen Han, Tong Wu, Yongqing Fu, Qingsheng Wu, Ming Wen   +6 more
wiley   +1 more source

The Concept of Unilateral Cleft Lip Repair

Journal of Plastic and Reconstructive Surgery, 2023
Surgical treatment of unilateral cleft lip is a difficult procedure, partly because many anatomical variants exist. The cleft lip has no excess tissue; hence, tissue from the cleft side cannot reach the normal side, even if all white lip tissue from the ...
Hitoshi Nemoto, Noriyoshi Sumiya
doaj  

Pilot epidemiological study of cleft lip and/or palate inh Kota Kinabalu, Sabah

Asian Journal of Medical Sciences, 2013
Objective: To identify number of cases and the type of cleft lip and/or palate managed in government tertiary center (Queen Elizabeth Hospital) in Kota Kinabalu; and to analyze the associative factors of cleft lip and/or palate.
Chai Siew Cheng
doaj   +1 more source

Ear- and hearing-related impact on quality of life in children with cleft palate : development and pretest of a health-related quality of life (HRQOL) instrument

, 2019
Objectives: To investigate to what extent middle ear problems and associated hearing loss affect quality of life (QoL) of children born with a cleft palate. Methods: Fifty-five children aged between 6 and 18 years, born with non-syndromic cleft palate +/
De Leenheer, Els, De Paepe, Justine, Dochy, Frederick, Van Hoecke, Helen, Willems, Sara   +4 more
core   +2 more sources