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Clinics in Plastic SurgeryThe primary function of the palate is to separate the nasal and oral cavities and facilitate the production of normal speech. The velar levator veli palatini (LVP) muscular sling is the palate speech motor. In the cleft palate, the LVP muscles are aberrantly sagittally oriented, which prevents their normal cranial, posterior, and lateral pull on the ...
Phalke N, Goldman JJ.
europepmc +7 more sources
Epidemiology, Etiology, and Treatment of Isolated Cleft Palate
Frontiers in Physiology, 2016 Isolated cleft palate (CPO) is the rarest form of oral clefting. The incidence of CPO varies substantially by geography from 1.3 to 25.3 per 10,000 live births, with the highest rates in British Columbia, Canada and the lowest rates in Nigeria, Africa ...
Madeleine L Burg +2 more
exaly +2 more sources
Orofacial Clefts: Genetics of Cleft Lip and Palate
Genes, 2023 Orofacial clefting is considered one of the commonest birth defects worldwide. It presents as cleft lip only, isolated cleft palate or cleft lip and palate.
Arwa Babai, M. Irving
semanticscholar +1 more source
Journal of Personalized Medicine, 2022 Cleft lip and cleft palate has one of the highest incidences in the malformations of the oral cavity, that varies between populations. The background underlying the issue of cleft lip and palate is multifactorial and greatly depends on the genetic ...
A. Paradowska-Stolarz +2 more
semanticscholar +1 more source
Orofacial Cleft Frequency Differences Depending on Geographic Origin: Coast vs. Inland
Frontiers in Dental Medicine, 2021 Objective: Cleft lip and/or palate is the most common congenital anomaly in a human face, with a multifactorial and complex etiology. Although many studies have been developed, the role of the environment is still unclear.
Alexandre Rezende Vieira +9 more
doaj +1 more source
Jurnal Rekonstruksi dan Estetik, 2020 Highlights: • The study's outcomes reveal favorable results regarding nasal enhancement following rhinoplasty, disparities in surgical choices, and variations in patient gender distribution.
Devyana Enggar Taslima +4 more
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Non-syndromic Cleft Palate: An Overview on Human Genetic and Environmental Risk Factors
Frontiers in Cell and Developmental Biology, 2020 The epithelial and mesenchymal cells involved in early embryonic facial development are guided by complex regulatory mechanisms. Any factor perturbing the growth, approach and fusion of the frontonasal and maxillary processes could result in orofacial ...
M. Martinelli +3 more
semanticscholar +1 more source
口腔疾病防治, 2023 Objective To explore the preventive effect of nicotinamide (NAM) on cleft palate induced by all-trans retinoic acid (RA), to provide research evidence for the prevention of cleft palate.
LI Guowei, TANG Shijie
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Cleft of lip and palate: A review
Journal of Family Medicine and Primary Care, 2020 Cleft of lip and palate are most common serial congenital anomalies to affect the orofacial region . It can occur isolated or together in various combination and/or along with other congenital deformities particularly congenital heart diseases.
Tarun Vyas +5 more
semanticscholar +1 more source
Tratamiento quirúrgico de insuficiencia velofaringea en pacientes con sÃndrome velo cardio facial
Gaceta Médica de México, 2023 Introducción: Insuficiencia velofaríngea (IVF) significa que el esfínter velofaríngeo (EVF) no logra sellar la comunicación entre cavidades nasales y tracto vocal situado inferiormente durante el habla.
Pablo-Antonio Ysunza, Matthew Rontal
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