Results 191 to 200 of about 1,664 (287)

“Activation‐Resistance Elimination” Regulation by Lanthanide/Transition Metal Ion‐Coordinated Nanostructures Intensifies Cuproptosis and Tumor Immunotherapy

Advanced Materials, EarlyView.
The lanthanide/transition metal ion coordination nanoparticles, La‐Cu@Lap/IWR‐1, with optimized coordination, have been proven to achieve remarkable results in realizing comprehensive tumor cuproptosis through efficient cuproptosis activation and multidimensional resistance elimination, thereby synchronously realizing the synergistic antitumor effects ...
Junrong Wang, Mengqian Xu, Huaping Zhao, Yulin Xie, Guoqing Zhu, Haoze Li, Qianqian Sun, Yong Lei, Chunxia Li   +8 more
wiley   +1 more source

Go-Along Virtual INTERview (GVIv): A Novel Nurse-Led Qualitative Method for Exploring Neighborhood Lived Experience and Health. [PDF]

Glob Qual Nurs Res
McClellan L, Emezue CN, Reed M, Schroeder K, Ruppar T.   +4 more
europepmc   +1 more source

ELSIE CLEWS PARSONS: II [PDF]

American Anthropologist, 1943
openaire   +1 more source

Blending With Insulating Polymers Enables Stable Anti‐Ambipolar Characteristics in n‐Type Organic Mixed‐Conductors for Heterogeneous Spiking Neurons

Advanced Materials, EarlyView.
A polymer blend of n‐type OMIEC P(gNDI‐gT2) with insulating PMMA yields mechanically stabilized, anti‐ambipolar organic electrochemical transistors (OECTs) with tunable ionic‐electronic transport. This blending allows low‐power, fast‐spiking heterogeneous Hodgkin–Huxley neurons, enabling biomimetic frequency deconvolution and reservoir computing, which
Zachary Laswick, Ariel Lifer, Catherine Beaumont, Liad Hayoun, Priscila Cavassin, Zeinab Hamid, Dilara Meli, William Dupont, Lincoln J. Lauhon, Iain McCulloch, Gitti L. Frey, Giovanni Maria Matrone, Jonathan Rivnay   +12 more
wiley   +1 more source

Programmable Microgel Degradation in Dynamic Granular Hydrogels Guides Extracellular Matrix Assembly During Tissue Repair

Advanced Materials, EarlyView.
This study reports on the chemical modification of hyaluronic acid to create hydrogels with hydrolytic degradability ranging from 2–28 days. Granular hydrogels that undergo timed degradation to increase porosity enhance cell invasion and provisional ECM remodeling in a muscle injury model, leading to reduced fibrosis and improved regeneration ...
Zhiyuan Chen, Tuba Marjan, Xinyue Lu, Nicole E. Mertens, Keira Vesy, Dean E. Stornello, James F. Markworth, Taimoor H. Qazi   +7 more
wiley   +1 more source

A Retinal Matrix Stiffening Model Reveals FAK‐Dependent Mechanotransduction in Pericytes Underlies Vascular Destabilization

Advanced Materials, EarlyView.
In this study, we show that retinal matrix stiffness is increased in diabetic mice. Using engineered human vascular models with controlled matrix stiffness, we demonstrate that stiffening activates focal adhesion kinase (FAK) signaling in pericytes, suppresses Notch signaling, and disrupts vascular morphology.
Emily Warren, Alex Wu, Lucas Ramirez, Yaqing Huang, Connor Amelung, Sophia Saxonhouse, Sharon Gerecht   +6 more
wiley   +1 more source

A Noninvasive Approach to Study Localized Forces in 3D Epithelia

Advanced Materials, EarlyView.
Epithelial morphogenesis depends on dynamic mechanical coupling between adhesion complexes and the cytoskeleton, yet its regulation in polarized 3D tissues remains elusive. We developed a noninvasive strategy using cell‐like elastic microbeads to quantify local forces in intact epithelia.
Niels Gouirand, Muhamet Ibrahimi, Claire Valotteau, Brice Lecouffe, André Le Bivic, Dominique Massey‐Harroche, Felix Rico, Matthias Merkel, Delphine Delacour, Elsa Bazellières   +9 more
wiley   +1 more source

Meta-core outcome set for randomized trials and clinical practice for curative surgical oncology: patient and healthcare consensus statement. [PDF]

BJS Open
Tay J, Blazeby J, Devane D, Loke Y, Lowery A, O'Neill A, Robinson C, Steele C, Alkhaffaf B, Kirkham J.   +9 more
europepmc   +1 more source

Amphiphilic Non‐Isocyanate Polyurethane Coatings With Tunable Antifouling and Fouling‐Release Performance: A Log‐Ratio Assessment Framework

Advanced Materials Interfaces, EarlyView.
Amphiphilic non‐isocyanate polyurethane (NIPU) coatings containing reactive hydrophobic poly(dimethylsiloxane) (PDMS) and hydrophilic methoxy poly(ethylene glycol) (MPEG) prepolymers for marine antifouling (AF) and fouling‐release (FR) applications were investigated. The coatings were evaluated with a set of representative marine foulants.
Nastaran Shahzadeh, Shane J. Stafslien, Lyndsi J. VanderWal, John A. Finlay, Peter Allen, Anthony S. Clare, Ivan Hevus, Dean C. Webster   +7 more
wiley   +1 more source