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Copper‐Free Click Chemistry: Applications in Drug Delivery, Cell Tracking, and Tissue Engineering

Advances in Materials, 2021
Traditionally, organic chemical reactions require organic solvents, toxic catalysts, heat, or high pressure. However, copper‐free click chemistry has been shown to have favorable reaction rates and orthogonality in water, buffer solutions, and ...
H. Y. Yoon   +4 more
semanticscholar   +1 more source

Click Chemistry with Polysaccharides

Macromolecular Rapid Communications, 2006
AbstractSummary: The copper‐catalyzed Huisgen reaction as a typical example of click chemistry was realized with the polysaccharide cellulose for the first time. The generality, selectivity, and the efficiency of click chemistry perfectly fit the requirements of polysaccharide modification, which is demonstrated by the introduction of triazole‐spacer ...
Claudia Hänsch   +2 more
openaire   +2 more sources

Click Chemistry with Ynamides.

ChemInform, 2006
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Jean-Christophe Cintrat   +1 more
openaire   +3 more sources

Click chemistry at the microscale

The Analyst, 2019
This manuscript reviews recent developments in click chemistry in microscale systems.
Tingting Hong   +3 more
openaire   +3 more sources

Ultrafast Click Chemistry with Fluorosydnones

Angewandte Chemie International Edition, 2016
AbstractWe report the synthesis and reactivity of 4‐fluorosydnones, a unique class of mesoionic dipoles displaying exquisite reactivity towards both copper‐catalyzed and strain‐promoted cycloaddition reactions with alkynes. Synthetic access to these new mesoionic compounds was granted by electrophilic fluorination of σ‐sydnone PdII precursors in the ...
Liu, Hui   +13 more
openaire   +6 more sources

Click chemistry for the synthesis of biobased polymers and networks derived from vegetable oils

, 2021
As we live in a time of heightening environmental issues, materials science is required to prepare sustainable polymers through green chemistry ideals. Vegetable oils and their fatty acid derivatives are well regarded for their use in polymer chemistry ...
Khantutta-Kim Tremblay-Parrado   +2 more
semanticscholar   +1 more source

The impact of click chemistry in medicinal chemistry

Expert Opinion on Drug Discovery, 2012
The copper(I)-catalyzed 1,3-dipolar cycloaddition of alkynes and azides to form 1,2,3-triazoles is the most popular reaction in click chemistry. This reaction is also near-perfect, in terms of its robustness, due to the high degree of reliability and complete specificity.
Peng George Wang   +4 more
openaire   +3 more sources

The growing applications of click chemistry

Chem. Soc. Rev., 2007
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Moses, J. E., Moorhouse, A. D.
openaire   +5 more sources

Visible-Light-Mediated Click Chemistry for Highly Regioselective Azide-Alkyne Cycloaddition via Photoredox Electron-Transfer Strategy.

Chemistry, 2020
"Click" chemistry is focused on the development of highly selective reactions utilizing simple precursors for the exquisite synthesis of molecules. Undisputedly, the Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) is one of the most valuable examples ...
Zhengguang Wu   +6 more
semanticscholar   +1 more source

Click chemistry to functionalise peptidomimetics

Tetrahedron Letters, 2006
Sharpless modified Huisgen's [2+3] cycloaddition of azide and acetylenic derivatives was employed as an efficient and simple method to conjugate azabicycloalkane amino acids, mimics of a homoSer-Pro dipeptide, with biologically relevant partners.
Leonardo Manzoni   +5 more
openaire   +2 more sources

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