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Copper‐Free Click Chemistry: Applications in Drug Delivery, Cell Tracking, and Tissue Engineering
Advances in Materials, 2021Traditionally, organic chemical reactions require organic solvents, toxic catalysts, heat, or high pressure. However, copper‐free click chemistry has been shown to have favorable reaction rates and orthogonality in water, buffer solutions, and ...
H. Y. Yoon+4 more
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Click Chemistry with Polysaccharides
Macromolecular Rapid Communications, 2006AbstractSummary: The copper‐catalyzed Huisgen reaction as a typical example of click chemistry was realized with the polysaccharide cellulose for the first time. The generality, selectivity, and the efficiency of click chemistry perfectly fit the requirements of polysaccharide modification, which is demonstrated by the introduction of triazole‐spacer ...
Claudia Hänsch+2 more
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Click Chemistry with Ynamides.
ChemInform, 2006AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Jean-Christophe Cintrat+1 more
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Click chemistry at the microscale
The Analyst, 2019This manuscript reviews recent developments in click chemistry in microscale systems.
Tingting Hong+3 more
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Ultrafast Click Chemistry with Fluorosydnones
Angewandte Chemie International Edition, 2016AbstractWe report the synthesis and reactivity of 4‐fluorosydnones, a unique class of mesoionic dipoles displaying exquisite reactivity towards both copper‐catalyzed and strain‐promoted cycloaddition reactions with alkynes. Synthetic access to these new mesoionic compounds was granted by electrophilic fluorination of σ‐sydnone PdII precursors in the ...
Liu, Hui+13 more
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Click chemistry for the synthesis of biobased polymers and networks derived from vegetable oils
, 2021As we live in a time of heightening environmental issues, materials science is required to prepare sustainable polymers through green chemistry ideals. Vegetable oils and their fatty acid derivatives are well regarded for their use in polymer chemistry ...
Khantutta-Kim Tremblay-Parrado+2 more
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The impact of click chemistry in medicinal chemistry
Expert Opinion on Drug Discovery, 2012The copper(I)-catalyzed 1,3-dipolar cycloaddition of alkynes and azides to form 1,2,3-triazoles is the most popular reaction in click chemistry. This reaction is also near-perfect, in terms of its robustness, due to the high degree of reliability and complete specificity.
Peng George Wang+4 more
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The growing applications of click chemistry
Chem. Soc. Rev., 2007AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Moses, J. E., Moorhouse, A. D.
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Chemistry, 2020
"Click" chemistry is focused on the development of highly selective reactions utilizing simple precursors for the exquisite synthesis of molecules. Undisputedly, the Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) is one of the most valuable examples ...
Zhengguang Wu+6 more
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"Click" chemistry is focused on the development of highly selective reactions utilizing simple precursors for the exquisite synthesis of molecules. Undisputedly, the Cu(I)-catalyzed azide-alkyne cycloaddition (CuAAC) is one of the most valuable examples ...
Zhengguang Wu+6 more
semanticscholar +1 more source
Click chemistry to functionalise peptidomimetics
Tetrahedron Letters, 2006Sharpless modified Huisgen's [2+3] cycloaddition of azide and acetylenic derivatives was employed as an efficient and simple method to conjugate azabicycloalkane amino acids, mimics of a homoSer-Pro dipeptide, with biologically relevant partners.
Leonardo Manzoni+5 more
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