Results 231 to 240 of about 2,234,265 (385)

Macrocyclic Molecular Glues for the 14‐3‐3/ChREBP Interaction: Affinity and Cooperativity in an Inverse Relationship

open access: yesAngewandte Chemie, EarlyView.
Macrocycles are effective molecular glues to stabilize the 14‐3‐3/ChREBP interaction. Linker length modulation uncovered an inverse correlation between the macrocycle binding affinity to 14‐3‐3 and its cooperativity in 14‐3‐3/ChREBP stabilization.
Marloes A. M. Pennings   +7 more
wiley   +1 more source

Rethinking brachycephaly: Anatomical implications and health considerations in lagomorphs

open access: yesThe Anatomical Record, EarlyView.
Abstract Brachycephaly in domestic rabbits is increasingly perceived by welfare organizations as associated with significant health complications, particularly oral pathologies. Despite this perception, comparative anatomical research into rabbit brachycephaly is limited compared to that of dogs and cats, compelling an in‐depth examination of its ...
Helaina Cressy   +3 more
wiley   +1 more source

“We might be put into situations we are uncomfortable with, but not exactly told how to deal with them”: Health professional students' experiences questioning low‐value care practices during work‐integrated learning

open access: yesAnatomical Sciences Education, EarlyView.
Abstract Health professions students often observe and practice alongside supervising health professionals during work‐integrated learning (WIL) to develop essential capabilities. While students may encounter practices they interpret as low‐value care during WIL, many hesitate to question or challenge these practices.
Melanie K. Farlie   +7 more
wiley   +1 more source

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