Results 81 to 90 of about 2,234,265 (385)

Thermally Gated Dual‐Cascade Nanozyme for Enhanced Mild‐Temperature Photothermal Therapy

Advanced Science, EarlyView.
A thermo‐responsive cascade nanozyme (Ru‐GOx‐PNN) synergistically enhances mild photothermal therapy by dual suppression of HSP70 through ROS‐induced lipid peroxidation and ATP depletion. This intelligent system effectively overcomes thermotolerance and amplifies apoptosis, offering a safe and precise strategy for tumor treatment.
Shuyu Wang, Shenghui Wang, Mengyuan Cao, Lulu Wang, Wei Jiang, Xiyun Yan, Ying Liu, Bing Jiang   +7 more
wiley   +1 more source

Modeling the population health impact of accurate and inaccurate perceptions of harm from nicotine

Harm Reduction Journal
Background Scientific evidence clearly demonstrates that inhaling the smoke from the combustion of cigarettes is responsible for most of the harm caused by smoking, and not the nicotine. However, a majority of U.S.
Thaddaeus Hannel, Lai Wei, Raheema S. Muhammad-Kah, Edward G. Largo, Mohamadi Sarkar   +4 more
doaj   +1 more source

Membralin Assembles a MAN1B1–VCP Complex to Target Foreign Glycoproteins from the Endoplasmic Reticulum to Lysosomes for Degradation

Advanced Science, EarlyView.
This study identifies Membralin as an ER‐phagy receptor that recruits MAN1B1 and VCP to form a selective ERLAD complex. By sensing dense N‐glycan clusters on viral fusion glycoproteins, this ubiquitin‐independent pathway directs SARS‐CoV‐2 spike, Ebola GP, influenza HA, and HIV‐1 Env to lysosomal degradation, thereby limiting viral infectivity ...
Jing Zhang, Xiaoran Lu, Sunan Li, Tao Wang, Iqbal Ahmad, Yong‐Hui Zheng   +5 more
wiley   +1 more source

Preventable in-hospital deaths and years of life lost were uncommon among patients in a Finnish secondary teaching hospital

Archives of Public Health
Background Despite quality standards and trained personnel, deaths caused by adverse events occur in healthcare. Estimates of in-hospital deaths caused by avoidable harm are contradictory. Old age and comorbidities increase the risk of death from adverse
Saara Ketola, Heli Ylihärsilä, Peter Nieminen, Auvo Rauhala, Tuija S. Ikonen   +4 more
doaj   +1 more source

In Solitary Rabbits, Does the Presence or Absence of a Mirror Affect Stress, Fear and Anxiety?

Veterinary Evidence, 2019
There is an erratum to this paper published in Veterinary Evidence Vol 4, Issue 2 (2018): http://dx.doi.org/10.18849/ve.v4i2.262PICO questionIn solitary rabbits, does the presence or absence of a mirror affect stress, fear and anxiety?Clinical bottom ...
Rebecca Schofield
doaj   +1 more source

Game-Theoretic Pricing and Selection with Fading Channels

, 2017
We consider pricing and selection with fading channels in a Stackelberg game framework. A channel server decides the channel prices and a client chooses which channel to use based on the remote estimation quality.
Leong, Alex S., Ni, Yuqing, Quevedo, Daniel E., Shi, Ling   +3 more
core   +2 more sources

Genetic Control of Tissue Remodeling by a Non‐Coding SNP in ITGA8 Explains Carotenoid‐Based Color Polymorphism in Marine Mollusks

Advanced Science, EarlyView.
In this study, the orange‐muscle giant abalone (Haliotis gigantea) is used as a model to identify a non‐coding SNP that disrupts the interaction between ITGA8 pre‐mRNA and the splicing factor ILF2, leading to altered ITGA8 splicing. These splicing changes promote carotenoid accumulation in abalone muscle through the regulation of tissue remodeling ...
Xiaohui Wei, Wenzhu Peng, Zekun Huang, Bingye Yang, Yiyu Wu, Minzhen Han, Yi Wang, Bingling Peng, Guosheng Hu, Jiawei Hong, Guijia Liu, Linwei Nie, Yang Gan, Miaoqin Huang, Xuan Luo, Weiwei You, Wen Liu, Caihuan Ke   +17 more
wiley   +1 more source

Switching behavior and changes in smoking behavior by menthol cigarette preference and menthol heated tobacco product use among adults in the United States who smoke cigarettes: an actual use study

Harm Reduction Journal
Background Heated tobacco products (HTPs) deliver nicotine with significantly lower toxicant exposure relative to combustible cigarettes. HTPs may serve as viable tobacco harm reduction options for adults who smoke but are not able or interested in ...
Joshua L. Karelitz, Yisha He, Elizabeth Becker, Andrea Vansickel   +3 more
doaj   +1 more source

Erratum to: In Solitary Rabbits, Does the Presence or Absence of a Mirror Affect Stress, Fear and Anxiety?

Veterinary Evidence, 2019
Unfortunately the original version of the article had the following error.
Rebecca Schofield
doaj   +1 more source

3D‐Printed Ion‐Conductive Hydrogels with Tunable Mechanical–Electrical Properties for Multimodal Sign Language Recognition

Advanced Science, EarlyView.
This work successfully fabricated ion‐conductive hydrogels with low hysteresis and high conductivity using 3D printing technology. By adjusting the component ratios, the properties of the hydrogels can be tuned to meet diverse sensing requirements. Finally, a multimodal sensing sign language recognition system was constructed based on this hydrogel ...
Quan Hu, Longya Xiao, Peiqi Zhang, Qiurui Zhang, Guangsen Liu, Xinglin Qin, Zhuhui Yin, Xian Li, Yuling Wang, Hongjie Jiang   +9 more
wiley   +1 more source