Results 251 to 260 of about 1,346,506 (296)

Neddylation Targets and Stabilizes NLRP3 to Augment Inflammasome‐Mediated Colitis and Mood Disorder

Advanced Science, EarlyView.
NLRP3 inflammasome contributes to colitis and mood disorder. This study demonstrates that neddylation targets NLRP3 at K287, which hinders its interaction with K48‐linked ubiquitination E3 Trim31 and thereby stabilizes it. Neddylation blockade in myeloid cells and microglia mitigates DSS‐induced colitis and psychological stress‐induced anxiety‐like ...
Wenbin Gai, Mengyao Wu, Anbiao Wu, Zhaofei Jing, Zhenjie Ye, Jiayan Jin, Yaolin Zhang, Min Zhao, Genyu Liu, Xu Wang, Xiqin Yang, Jie Dong, Yunlu Xu, Jiyan Zhang   +13 more
wiley   +1 more source

Climate Change Can Generate Enemy-Free Space for Crop-Feeding Herbivores. [PDF]

Glob Chang Biol
Wyckhuys KAG, Pozsgai G, Finch EA, Seehausen ML, Zhang W, Gc YD.   +5 more
europepmc   +1 more source

Erratum: The Economics of 1.5°C Climate Change

, 2019
Simon Dietz, Alex Bowen, Baran Doda, Ajay Gambhir, Rachel Warren   +4 more
openalex   +1 more source

Midbrain PAG Astrocytes Modulate Mouse Defensive and Panic‐Like Behaviors

Advanced Science, EarlyView.
Astrocytes in the midbrain periaqueductal gray (PAG) dynamically encode threat intensity and shape defensive action selection in mice. Real‐time Ca2+ imaging reveals robust astrocytic activation during predator odor and CO2 exposure. Aberrant astrocytic Ca2+ overactivation disrupts goal‐directed escape, biases behavior toward freezing, and induces ...
Ellane Barcelon, Kyungchul Noh, Minkyu Hwang, Yoon‐Jung Kim, Unjin Lee, Yeon Joo Ryu, Je‐Kyung Ryu, Sang Beom Jun, Se‐Young Choi, Woo‐Hyun Cho, Sung Joong Lee   +10 more
wiley   +1 more source

Why climate action is an opportunity multiplier for mental health. [PDF]

World Psychiatry
Lawrance EL.
europepmc   +1 more source

Thermal Plasticity is Regulated by a Key MicroRNA During Range Expansion of an Invasive Fruit Fly

Advanced Science, EarlyView.
Populations at the invasion front of Bactrocera dorsalis adapt through reduced phenotypic and gene expression plasticity, a phenomenon likely to be driven by genetic assimilation. We identify a key miRNA‐mediated regulatory axis, in which miR‐276b post‐transcriptionally represses thw, a conserved chitin‐binding gene critical to the cold‐tolerance ...
Yan Zhao, Juntao Hu, Juan Du, Shaokun Guo, Youming Hou, Zhihong Li   +5 more
wiley   +1 more source

Right-scaling and scaling-up knowledge co-production for decarbonization, climate-resilience and equity through [multilevel] metropolitan climate action planning

Environmental Research Letters
Anu Ramaswami
doaj   +1 more source

Hungary's Current Climate Conditions Converge With the North-Mediterranean of the 1980s: A Case Study in Mediterranean Ant Species New to Hungary. [PDF]

Ecol Evol
Csősz S, Laczi M, Herczeg G, Báthori F.   +3 more
europepmc   +1 more source

Alejandro Daly: bridging the gap between climate and health. [PDF]

Bull World Health Organ
europepmc   +1 more source