Results 171 to 180 of about 4,982,688 (286)

Microbes without borders: uniting societies for climate action. [PDF]

Sustain Microbiol
Lennon JT, Bittleston LS, Chen Q, Cooper VS, Fernández J, Gilbert JA, Häggblom MM, Harper LV, Jansson JK, Jiao N, Kuurstra EM, Peixoto RS, Rappuoli R, Schembri MA, Ventosa A, Vullo DL, Zhang C, Nguyen NK.   +17 more
europepmc   +3 more sources

Greening clubs- the role of sport in Ireland's approach to local climate action. [PDF]

Front Sports Act Living
Boyle E.
europepmc   +1 more source

Mr BMT Achieves Systemic Macrophage Replacement With Preservation of Tissue Homeostasis

Advanced Science, EarlyView.
Microglia replacement by bone marrow transplantation (Mr BMT) enables systemic replacement of tissue‐resident macrophages. Despite persistent macrophage and tissue remodeling across multiple organs, core biological functions and innate immune responses remain preserved, supporting long‐term maintenance of organismal homeostasis and the therapeutic ...
Yufei Xu, Miaozhan Zou, Yunshang Bai, Yang He, Zhihao Jin, Baozhi Yang, Jinjin Du, Pei Ouyang, Yuanyuan Cai, Yuheng Zhang, Bingying Du, Chengcheng Ge, Jian‐an Gong, Xiaoyu Li, Yuanyi Zheng, Jing Ding, Bo Peng, Yanxia Rao   +17 more
wiley   +1 more source

Chemoproteomic Identification of AKT2 as a Paclitaxel‐Binding Protein via C─C Bond‐Linked Probe PTX‐4 in Paclitaxel‐Resistant Breast Cancer

Advanced Science, EarlyView.
ABSTRACT Breast cancer remains one of the most prevalent malignancies among women, and taxane‐based chemotherapies such as paclitaxel and docetaxel are central to standard treatment regimens. However, drug resistance in breast cancer limits therapeutic efficacy and contributes to recurrence and metastasis.
Kai Wang, Yuqing Yuan, Wei Shen, Xiuxiu Yang, Xiaokang Wu, Haihua Zhou, Yi Hu, Qing Zhu   +7 more
wiley   +1 more source

Why climate action is an opportunity multiplier for mental health. [PDF]

World Psychiatry
Lawrance EL.
europepmc   +1 more source

What is Anticipatory Action

This video presents the key concepts around anticipatory action. Anticipatory Action in the Andes (AA-Andes) is a project aimed to strengthen the resilience of Andean communities to hydrometeorological hazards in Peru, Bolivia and Ecuador.
Action, Practical
core  

Delayed Action and Uncertain Targets. How Much Will Climate Policy Cost? [PDF]

Despite the growing concern about actual on-going climate change, there is little consensus about the scale and timing of actions needed to stabilise the concentrations of greenhouse gases.
Alessandra Sgobbi, Carlo Carraro, Valentina Bosetti, Massimo Tavoni   +3 more
core  

Disrupted TFEB/GDNF–cAMP/ATP Coupling Underlies Astrocytic Dysfunction and Depression in LRRK2 G2019S Parkinson's Mice

Advanced Science, EarlyView.
ABSTRACT The LRRK2 G2019S mutation, a Parkinson's disease–linked variant, has been associated with depression‐like phenotypes, but mechanisms remain unclear. We chart age‐dependent behavioral changes and astrocyte reactivity in G2019S mice and define a pathway connecting LRRK2 to TFEB/GDNF signaling, cellular energetics, and inflammation.
Longping Yao, Maryam Hatami, Sumeyye Koc, Qing Jiang, Thomas Skutella, Yuanfeng Zhang   +5 more
wiley   +1 more source

Multiple roles of business for climate action. [PDF]

iScience
Hampton S, Byfuglien A, Eadson W, Latter B, Hardy-Jones B, Sugar K, Bamford H, Blundel R.   +7 more
europepmc   +1 more source

Adult Sex Ratio as a Demographic Feedback Linking Mating Systems, Parental Care, and Evolution

Advanced Science, EarlyView.
Breeding systems are some of the most diverse social behavior, and our team is investigation the evolutionary causes of this diversity. This review summarises our research carried out at the University of Bath. We argue that demographic components of wild populations, especially the adult sex ratio, plays a key role driving breeding system variation ...
Tamás Székely, Oscar G. Miranda
wiley   +1 more source