Results 41 to 50 of about 879,580 (295)

Assessment of governance strategies for climate adaptation in Flanders / Belgium [PDF]

open access: yes, 2010
Climate discourse in recent decades has mainly focused on the issue of mitigation. Through a better understanding and assessment of climate challenges, adaptation arises as a complementary strategy to mitigation.
Allaert, Georges   +2 more
core   +1 more source

Women and water management in times of climate change: participatory and inclusive processes [PDF]

open access: yes, 2013
This paper focuses on community engagement, and particularly the inclusion of women, in water management as a response to climate change. Addressing water-related problems is central to climate change adaptation, and civil society, marginalized ...
Figueiredo, P.   +1 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Existing evidence on the effects of climate variability and climate change on ungulates in North America: a systematic map

open access: yesEnvironmental Evidence
Background Climate is an important driver of ungulate life-histories, population dynamics, and migratory behaviors. Climate conditions can directly impact ungulates via changes in the costs of thermoregulation and locomotion, or indirectly, via changes ...
Katherine C. Malpeli   +6 more
doaj   +1 more source

Integrating climate in Ugandan health and subsistence food systems: where diverse knowledges meet

open access: yesBMC Public Health, 2020
Background The effects of food insecurity linked to climate change will be exacerbated in subsistence communities that are dependent upon food systems for their livelihoods and sustenance. Place-and community-based forms of surveillance are important for
Bianca van Bavel   +7 more
doaj   +1 more source

Motivations for local climate adaptation in Dutch municipalities: climate change impacts and the role of local-level government [PDF]

open access: yes, 2009
The local government level is considered to be crucial in preparing society for climate change impact. Yet little is known about why local authorities do or do not take action to adapt their community for climate change impacts.
Berg, Maya M. van den
core   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Indigenous knowledge in climate adaptation planning: reflections from initial efforts

open access: yesFrontiers in Climate
There are increasing calls to incorporate indigenous knowledge (IK) into climate adaptation planning (CAP) and related projects. However, given unique attributes of IK and the positionality of tribal communities to scientific research, several ...
Tony W. Ciocco   +5 more
doaj   +1 more source

Climate change impacts and relevance of smallholder farmers’ response in arid and semi-arid lands in Kenya

open access: yesScientific African, 2021
In the recent decades, extreme weather events have increased in frequency, intensity and magnitude threatening and increasing the vulnerability of rural livelihoods particularly in the arid and semi-arid lands.
Dorcas N. Kalele   +3 more
doaj   +1 more source

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