Results 111 to 120 of about 3,469,595 (342)

Considerations for Issues of Regression to the Mean and Contextual Effects in Clinical Trials for Pain in Rheumatic Diseases

open access: yesArthritis Care &Research, EarlyView.
Recently, there has been growing discussion about how to best assess pain in clinical trials in rheumatic diseases. Reliable measurement of pain outcomes is essential for accurately determining the effectiveness of treatments. Although pain intensity is the most common measure of change in pain trials, other pain‐related measures, such as pain ...
Yen T. Chen   +4 more
wiley   +1 more source

Zooming in on climate change data [PDF]

open access: yes, 2014
The agricultural sector will be hit hard by climate change. More than 265 million people are facing a five percent decrease in growing season duration in the next 40 years due to an increasingly variable and hotter climate sweeping across the globe ...
CGIAR Research Program on Climate Change, Agriculture and Food Security
core  

Assessment of Pain Types in Recently Diagnosed Patients With Inflammatory Arthritis

open access: yesArthritis Care &Research, EarlyView.
Objective Up to 40% of patients with inflammatory arthritis (IA) experience persistent pain, traditionally thought to be associated with a shift from peripherally to centrally mediated pain during the disease course in some patients. We assessed sensory profiles of recently diagnosed individuals with IA, hypothesizing that pain reported at this early ...
Zoe Rutter‐Locher   +8 more
wiley   +1 more source

Climate Change Policy [PDF]

open access: yes
Having risen from relative obscurity as few as ten years ago, climate change now looms large among environmental policy issues. Its scope is global; the potential environmental and economic impacts are ubiquitous; the potential restrictions on human ...
Shogren, Jason, Toman, Michael
core  

Farmers’ video testimonials to scale out climate-smart agriculture [PDF]

open access: yes, 2015
CCAFS has documented farmers’ testimonials on climate-smart agriculture through several short films. The films form an important repository of the various interventions being used in Climate-Smart Villages in Bihar and Haryana.
CGIAR Research Program on Climate Change, Agriculture and Food Security
core  

Beyond Inflammation: Why Understanding the Brain Matters in Inflammatory Arthritis

open access: yesArthritis Care &Research, EarlyView.
Persistent pain remains a major challenge in inflammatory arthritis, even when joint inflammation is well controlled. Pain and associated symptoms such as fatigue cannot be explained by peripheral inflammation alone but reflect altered central pain processing. These changes may arise through “top‐down” mechanisms, reflecting pre‐existing dysfunction in
Eoin M. Kelleher   +2 more
wiley   +1 more source

Systematic review and meta-analysis of ex-post evaluations on the effectiveness of carbon pricing

open access: yesNature Communications
Today, more than 70 carbon pricing schemes have been implemented around the globe, but their contributions to emissions reductions remains a subject of heated debate in science and policy.
Niklas Döbbeling-Hildebrandt   +14 more
doaj   +1 more source

A global baseline for changing farming practices [PDF]

open access: yes, 2015
Tracking change is how you stay on the path to a goal. That’s why the CGIAR Research Program on Climate Change, Agriculture and Food Security (CCAFS) wants to measure how agricultural practices are evolving in response to climate change and other ...
CGIAR Research Program on Climate Change, Agriculture and Food Security
core  

Impact of long-term climate change on flow regime in a Mediterranean basin

open access: gold, 2022
Anna Maria De Girolamo   +3 more
openalex   +1 more source

Pharmacokinetics, Pharmacodynamics, and Safety of Subcutaneous Belimumab in Pediatric Patients with Systemic Lupus Erythematosus: A Multicenter, Open‐Label Trial

open access: yesArthritis Care &Research, Accepted Article.
Objective This study aimed to characterize the pharmacokinetics, pharmacodynamics, safety, and exploratory efficacy of subcutaneous belimumab in pediatric patients with active systemic lupus erythematosus (SLE) receiving standard therapy. Methods This single‐arm, multicenter, open‐label trial (GSK study 200908; NCT04179032) used three‐weight‐band ...
Hermine I. Brunner   +14 more
wiley   +1 more source

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