Results 321 to 330 of about 16,968,314 (408)

Teacher Ideology and the Climate for Change

, 1988
Mike Long
openalex   +2 more sources

Activation of Glutamatergic Neurons in the Supramammillary Nucleus Promotes the Recovery of Consciousness under Sevoflurane Anesthesia

Advanced Science, EarlyView.
Selective lesioning of SuM glutamatergic neurons promoted the induction of and delayed emergence from sevoflurane anesthesia and increased sevoflurane sensitivity. Optogenetic stimulation of SuM glutamatergic neurons or the SuM‐MS projection promoted behavioral arousal and cortical activation under steady‐state sevoflurane anesthesia and reduced the ...
Jiayan Li, Yehui Wu, Yihan Wang, Yumin Wu, Rong Hu, Si Long, Wenqi Huang, Liming Nie, Zhongxing Wang   +8 more
wiley   +1 more source

Climate change is leading to an ecological trap in a migratory insect. [PDF]

Proc Natl Acad Sci U S A
Zhang SY, Zhang YY, Yang F, Zhou C, Shen HM, Wang BB, Zeng J, Reynolds DR, Chapman JW, Hu G.   +9 more
europepmc   +1 more source

Shrimp Virus Regulates ROS Dynamics via the Nrf2 Pathway to Facilitate Viral Replication

Advanced Science, EarlyView.
Viruses manipulate host ROS as a strategy to achieve successful infection. WSSV exploits Nrf2 pathway to maintain ROS homeostasis and establishes a positive feedback loop to facilitate WSSV replication. Wsv220 competitively binds to Keap1 to activate Nrf2. Nrf2 up‐regulates LvG6PDH to produce more NADPH and GSH to eliminate excessive ROS.
Honghui He, Kai Yuan, Junming Pan, Shaoping Weng, Chaozheng Li, Yihong Chen, Jianguo He   +6 more
wiley   +1 more source

RNF112 Facilitates Ubiquitin‐Mediated Degradation of c‐Myc, Suppressing Proliferation, Migration and Lipid Synthesis in Bladder Cancer

Advanced Science, EarlyView.
RNF112, an E3 ubiquitin ligase, is markedly reduced in bladder cancer (BLCA). It curbs BLCA cell proliferation, migration, and lipid production primarily by enhancing ubiquitin‐dependent degradation of c‐Myc. This degradation inhibits c‐Myc's role in upregulating ACLY, a crucial enzyme for lipid synthesis, highlighting RNF112's potential as a ...
Kangping Xiong, Siming Chen, Huimin Xu, Sheng Tu, Hong Weng, Yejinpeng Wang, Mingxing Li, Jingtian Yu, Kaiyu Qian, Lingao Ju, Yi Zhang, Yu Xiao, Xinghuan Wang, Gang Wang   +13 more
wiley   +1 more source

Climate change and gendered vulnerability: A systematic review of women's health. [PDF]

Womens Health (Lond)
Anjum G, Aziz M.
europepmc   +1 more source

Mucous Permeable Nanoparticle for Inducing Cuproptosis‐Like Death In Broad‐Spectrum Bacteria for Nebulized Treatment of Acute Pneumonia

Advanced Science, EarlyView.
Copper‐based nanoparticles doped with BSO, and modified with PEG, not only can it increase the retention ability and mucosal penetration ability in the lungs, but also induce cuproptosis‐like death in bacteria and inhibit bacterial TCA cycle. It can also inhibit bacterial quorum sensing, clear biofilms, reduce bacterial virulence, and thus exert ...
Huiqun Hu, Shiyuan Hua, Feng Lu, Wenting Zhang, Zengwen Zhang, Jiarong Cui, Xiaoyue Lei, Jingyan Xia, Feng Xu, Min Zhou   +9 more
wiley   +1 more source

Identification of climate change hotspots in the Mediterranean. [PDF]

Sci Rep
Lazoglou G, Papadopoulos-Zachos A, Georgiades P, Zittis G, Velikou K, Manios EM, Anagnostopoulou C.   +6 more
europepmc   +1 more source

Amazon Deforestation and Climate Change

, 1990
J. Shukla, Carlos A. Nobre, P. J. Sellers   +2 more
openalex   +2 more sources

Chchd10: A Novel Metabolic Sensor Modulating Adipose Tissue Homeostasis

Advanced Science, EarlyView.
Chchd10 is a novel regulator of adipose tissue (AT) homeostasis upon excess energy intake. Rapid Chchd10 reduction in response to high‐fat diet induction promotes adipogenesis in subcutaneous AT to store excess energy. On the other hand, sustained Chchd10 reduction protects visceral AT from 4‐HNE‐induced adipocyte dysfunction, attenuating the ...
Xiaoping Wu, Zixuan Zhang, Jingjing Li, Jiuyu Zong, Lufengzi Yuan, Lingling Shu, Lai Yee Cheong, Xiaowen Huang, Mengxue Jiang, Zhihui Ping, Aimin Xu, Ruby L.C. Hoo   +11 more
wiley   +1 more source