Results 121 to 130 of about 61,855 (264)
Advanced Science, EarlyView.Chronic stress disrupts copper homeostasis and promotes copper accumulation in the prelimbic cortex, leading to astrocytic FDX1 upregulation. Elevated astrocytic FDX1 impairs calcium signaling, induces structural atrophy, and disrupts synaptic function, contributing to depressive‐like behaviors. Physical exercise reverses these alterations by restoring
Lina Gao +11 more
wiley +1 more source
A Modular PLUG‐IN Photosynthetic Chassis With Tunable Thermal Control for Mammalian Systems
Advanced Science, EarlyView.This work establishes a “plug‐in” chassis compatible with mammalian systems that synchronizes growth, production, and cell‐wall re‐configuration, providing a versatile platform for photosynthetic bioproduction and microalgal synthetic biology. ABSTRACT Microalgae are promising photosynthetic platforms for high‐value compounds, yet their industrial use ...
Qinhua Gan +13 more
wiley +1 more source
Advanced Science, EarlyView.An optimized single‐cell transcriptomic framework profiles over 60 000 cells to map the ovine rumen microbiome, partitioning the ecosystem into seven cross‐species functional clusters. In heat‐resistant hosts, a lineage‐specific metabolic shift in Anaerovibrio lipolyticus toward a highly glycolytic phenotype contributes to a “nutritional sparing ...
Sanbao Zhang +8 more
wiley +1 more source
Advanced Science, EarlyView.We present a chromosome‐level genome assembly of Siraitia grosvenorii and, through comparative genomics, uncover a conserved UGT73 tandem array driving triterpenoid saponin diversification in Cucurbitaceae. Crystalized SgUGT73AM30 further reveals the regioselectivity mechanism underlying its catalytic activity.
Guangyi Wang +13 more
wiley +1 more source
Legitimacy-building to establish climate services in Uganda's health system: The role of digital health platform. [PDF]
SSM Health SystOmiel PO +4 more
europepmc +1 more source
Adipocyte Myoglobin Is a Determinant of Energy Expenditure and a Potential Target to Limit Obesity
Advanced Science, EarlyView.Myoglobin, known as a muscle oxygen‐carrying protein, is shown to play a key role in fat cells that burn energy. Loss of myoglobin reduces the body's ability to generate heat and increases obesity risk, while restoring it improves metabolism. The study identifies myoglobin as a regulator of fat burning and a potential target to enhance energy ...
Christian Strehlau +22 more
wiley +1 more source
Can innovation strengthen resilient, just and sustainable health systems in disaster-prone settings? Insights from HSR2024. [PDF]
Health Policy PlanJalaghonia N, Huque R, Daniels D.
europepmc +1 more source
Advanced Science, EarlyView.High‐entropy doping of Co‐free Ni‐rich LiNiO2 cathodes is achieved through a scalable 3D mixing process. Multi‐element incorporation stabilizes the layered structure, alleviates Li/Ni disorder and electrode swelling, and enhances cycling stability. This approach underscores the potential of high‐entropy strategies to deliver structurally robust and ...
Seung Ri Kim +6 more
wiley +1 more source
The impact of urban climate governance on FDI: empirical evidence from the construction of climate-adaptive pilot cities. [PDF]
Sci RepDong A, Zhang B, Cao L.
europepmc +1 more source
, 2019 Climate change is one of the most widespread anthropogenic challenges affecting agriculture and agricultural production in the coffee agroforestry system, where its impacts on economic growth in general are still issues in debate. An adjustment to the actual or expected changes in the agricultural sector using different innovative adaptation strategies
Asayehegn, Kinfe +2 more
openaire +1 more source