Results 291 to 300 of about 467,454 (350)

PlantGFM: A Genomic Foundation Model for Discovery and Creation of Plant Genes

open access: yesAdvanced Science, EarlyView.
A plant genomic foundation model pre‐trained on 12 species enables both accurate gene prediction and de novo gene design. Through AI‐human knowledge screening, seven designed sequences showed transcriptional activity in plants, with two expressing stable proteins—demonstrating the first DNA‐RNA‐protein expression of LLM‐generated genes in plants and ...
Changhao Li   +10 more
wiley   +1 more source

SIRT6‐Mediated Deacetylation of ATF3 Promotes Silica‐Induced Lung Fibrosis by Enhancing its Nuclear Import via Binding to Importin α

open access: yesAdvanced Science, EarlyView.
SIRT6‐mediated ATF3 acetylation drives MGARP transcription and mitochondrial dysfunction in macrophages, promoting macrophage senescence and pulmonary fibrosis. Mechanistically, HSP70/Importin α competitively binds to ATF3, modulating its nuclear translocation.
Demin Cheng   +18 more
wiley   +1 more source

Thin‐Film Thermal Sensors on Chitosan Substrates for Sustainable Transient Electronics

open access: yesAdvanced Electronic Materials, EarlyView.
Fully transient thin‐film temperature sensors are realized on pure chitosan substrates using Mo‐based RTDs and a‐IGZO/Mo thermistors. The devices exhibit high sensitivity, mechanical flexibility, humidity‐aware operation, and complete dissolution in natural solvents.
Ahmed Rasheed   +14 more
wiley   +1 more source

The Effects of Transition to Renewable Energy on Climate Change Mitigation and Economic Development in Developing Nations

open access: green
Ph.D; Pastor Engr. (Dr.) Enoch Oyokunyi & Dr. Stephen Udezi. A.L. Ph.D. Prof. Okeke Gerald Ndubuisi; Professor Cynthia Amaka Obiorah; Engr. Prof. Theophilus Aku Ugah; Engr. Abubakar Rahmat Salihu; Prof. James Okoroma
openalex   +1 more source

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