Results 41 to 50 of about 16,680,932 (313)
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
Enhancing and optimization for efficient removal of nickel ions by modified activated carbon
Scientific ReportsThis study aims to enhance the adsorption capacity of activated carbon (AC) and optimize the cumulative effect of various operational parameters on the removal of Ni (II) ions, providing a comprehensive understanding of the removal process.
Shimaa M. Abdel-Moniem +3 more
doaj +1 more source
Changes in compound flood event frequency in northern and central Europe under climate change
Frontiers in Climate, 2023 The simultaneous occurrence of increased river discharge and high coastal water levels may cause compound flooding. Compound flood events can potentially cause greater damage than the separate occurrence of the underlying extreme events, making them ...
Philipp Heinrich +3 more
doaj +1 more source
Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
FEBS Open Bio, EarlyView.This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler +20 more
wiley +1 more source
Journal of Marine Science and EngineeringTropical cyclones typically weaken rapidly during poleward propagation due to decreasing sea surface temperatures and increasing vertical wind shear.
Chengjie Tian +5 more
doaj +1 more source
Climate change impacts on cultural heritage: A literature review
WIREs Climate Change, 2021 Climate change, as revealed by gradual changes in temperature, precipitation, atmospheric moisture, and wind intensity, as well as sea level rise and changes in the occurrence of extreme events, is already affecting cultural heritage sites.
Elena Sesana +4 more
semanticscholar +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel +8 more
wiley +1 more source
Climate Change and Climate Science [PDF]
Science, 2004 T here is a paradoxical gulf between the importance of Earth's climate and the level of public interest in it. To be sure, tornadoes, killer heat waves, and floods make the headlines, but it's important to remember that weather is not climate. Some of the public's confusion may relate to a certain failure to make that distinction, as in the occasional ...
openaire +2 more sources
Impact of Climate Change on Crops Adaptation and Strategies to Tackle Its Outcome: A Review
Plants, 2019 Agriculture and climate change are internally correlated with each other in various aspects, as climate change is the main cause of biotic and abiotic stresses, which have adverse effects on the agriculture of a region.
A. Raza +6 more
semanticscholar +1 more source