Results 81 to 90 of about 18,588,179 (359)

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Spatiotemporal Dynamics and Drivers of Wetland Change on Chongming Island (2000–2020) Using Deep Learning and Remote Sensing

Journal of Marine Science and Engineering
Using Landsat series imagery and the deep learning model CITNet, this study conducted high-accuracy classification and spatiotemporal change analysis of wetlands on Chongming Island from 2000–2020 and explored the driving mechanisms by integrating ...
An Yi, Yang Yu, Hua Fang, Jiajun Feng, Jinlin Ji   +4 more
doaj   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp, Ludwig Karrasch, Helena Breitenstein, Andreas Straube, Katharina Kamm   +4 more
wiley   +1 more source

INFLUENCE OF CLIMATE CHANGES ON WATER RESOURCES IN MOLDOVA [PDF]

Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry, 2012
The paper aims to analyze the current state of affairs with water resources in Moldova, the challenges it faces for its national human and economic development, having in mind that the water resources are quite limited in Moldova, which encounters ...
Violeta Ivanov
doaj  

Improved concrete properties to resist the saline water using environmental by-product

Water Science, 2013
This paper investigates the influence of using environmental by-product materials (silica fume and fly ash) in concrete on the chloride ion permeability of concrete.
Mohamed Anwar, Mahmoud Roushdi
doaj   +1 more source

Projected climate-induced faunal change in the western hemisphere [PDF]

, 2009
Climate change is predicted to be one of the greatest drivers of ecological change in the coming century. Increases in temperature over the last century have clearly been linked to shifts in species distributions.
Bartlein, Patrick J., Blaustein, Andrew R., Kareiva, Peter, Lawler, Joshua J., Maurer, Edwin P., Shafer, Sarah L., White, Denis   +6 more
core   +1 more source

Forest disturbances under climate change

Nature Climate Change, 2017
Forest disturbances are sensitive to climate. However, our understanding of disturbance dynamics in response to climatic changes remains incomplete, particularly regarding large-scale patterns, interaction effects and dampening feedbacks. Here we provide
R. Seidl, Dominik Thom, M. Kautz, D. Martin‐Benito, M. Peltoniemi, G. Vacchiano, J. Wild, D. Ascoli, M. Petr, Juha Honkaniemi, M. Lexer, V. Trotsiuk, P. Mairota, M. Svoboda, M. Fabrika, T. Nagel, C. Reyer   +16 more
semanticscholar   +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone, Freddy Chafota, Miguel E. Rentería, Randi J. Hagerman, Ellery Santos, Anna Atkinson, Nicholas G. Martin, Elsdon Storey, Danuta Z. Loesch   +8 more
wiley   +1 more source

Investigation the implications of climate change on crop water requirements in Western Nile Delta, Egypt

Water Science
Egypt is grappling with water shortage, with agriculture using about 80% of its water consumption. Climate change is only going to further complicate water availability and water consumption.
Mahmoud Roushdi
doaj   +1 more source

Bunker Cave stalagmites: an archive for central European Holocene climate variability [PDF]

, 2012
Holocene climate was characterised by variability on multi-centennial to multi-decadal time scales. In central Europe, these fluctuations were most pronounced during winter. Here we present a record of past winter climate variability for the last 10.8 ka
Fohlmeister, Jens, Gerdes, Axel, Immenhauser, Adrian, Mangini, Augusto, Mudelsee, Manfred, Richter, Detlev K., Riechelmann, Dana F. C., Riechelmann, Sylvia, Scholz, Denis, Schröder-Ritzrau, Andrea, Spötl, Christoph, Wackerbarth, Anne Katrin   +11 more
core   +2 more sources