Results 131 to 140 of about 862,694 (301)

Publisher Correction: Present and future Köppen-Geiger climate classification maps at 1-km resolution. [PDF]

Sci Data, 2020
Beck HE, Zimmermann NE, McVicar TR, Vergopolan N, Berg A, Wood EF.   +5 more
europepmc   +1 more source

Paving the Way to Elucidate Hg's Role in Tumorigenesis

Advanced Science, EarlyView.
Tumorigenesis can result from diverse environmental carcinogens. Among them, mercury—a lifelong bioaccumulative Group 2B carcinogen—has tumorigenic potential that remains poorly understood due to confounding co‐exposures and limited organ‐specific data.
Shouying Li, Rong Zhong, Zhenyang Yu, Hualing Fu, Jin Chen, Jia Wei, Ningwei Zhao, Le Qu, Tiantian Li, Wenli Tang, Huan Zhong   +10 more
wiley   +1 more source

Climate dynamics and fluid mechanics: Natural variability and related uncertainties

, 2010
The purpose of this review-and-research paper is twofold: (i) to review the role played in climate dynamics by fluid-dynamical models; and (ii) to contribute to the understanding and reduction of the uncertainties in future climate-change projections. To
Allen, Andronov, Anishchenko, Anishchenko, Anishchenko, Arnold, Arnold, Arnold, Arnold, Arnol’d, Bak, Bak, Berger, Berloff, Bouchet, Caraballo, Cessi, Chang, Chang, Charney, Coayla-Teran, Cong, Cong, Crauel, Da Costa, Denjoy, Dijkstra, Dijkstra, Dijkstra, Duan, Duan, Dubar, Eckmann, Eric Simonnet, Farrel, Feigenbaum, Feliks, Feliks, Ghil, Ghil, Ghil, Ghil, Gill, Grebogi, Guckenheimer, Guckenheimer, Held, Hillerbrand, Jiang, Jiang, Jin, Jin, Jung, Kaijser, Katok, Katsman, Kloeden, Kondrashov, Kravtsov, Kuksin, Kuznetsov, Langa, Li, Lin, Lin, Lin, Lorenz, Madden, Mañé, McWilliams, Meacham, Michael Ghil, Mickaël D. Chekroun, Mitchell, Moron, Nadiga, Neelin, Newhouse, Oseledets, Palis, Palmer, Pedlosky, Pedlosky, Peixoto, Plaut, Poincaré, Pope, Primeau, Robbin, Robert, Robinson, Saunders, Sell, Sheremet, Simonnet, Simonnet, Simonnet, Simonnet, Simonnet, Simonnet, Sinai, Smale, Smale, Speich, Stainforth, Stommel, Sushama, Sverdrup, Trefethen, Tziperman, Tziperman, Williams, Wunsch, Zmarrou   +113 more
core   +1 more source

Restriction of Individual Branched‐Chain Amino Acids has Distinct Effects on the Development and Progression of Alzheimer's Disease in 3xTg Mice

Advanced Science, EarlyView.
Protein restriction (PR) slows Alzheimer's disease (AD) in mice, and other benefits of PR are due to decreased branched‐chain amino acids (BCAAs). We show that restricting any BCAA has benefits, with sex‐ and BCAA‐specific impacts on pathology, molecular signaling, and cognition.
Reji Babygirija, Cara L. Green, Michelle M. Sonsalla, Izabelle Marie F. Le, Fan Xiao, Sarah Yandell, Mariah F. Calubag, Michaela E. Trautman, Anna Tobon, Ryan Matoska, Chung‐Yang Yeh, Charles I. Opara, Isaac Grunow, Diana Vertein, Sophia Schlorf, Bailey A. Knopf, Michael J. Rigby, David A. Harris, Mark P. Keller, Alan D. Attie, Luigi Puglielli, Cholsoon Jang, Dudley W. Lamming   +22 more
wiley   +1 more source

CRP Deficiency Rescues Periodontitis‐Induced Hippocampal Neurogenesis Impairment by Suppressing OPC‐Derived BMP4 Signaling in Rats

Advanced Science, EarlyView.
Chronic periodontitis elevates circulating CRP, which enters the hippocampus to upregulate BMP4 in oligodendrocyte precursor cells (OPCs), thereby impairing neurogenesis and inducing anxiety/depression‐like behaviors in rats. Counteracting this pathway, CRP deficiency helps confer functional resilience to OPCs.
Lingjie Li, Ping Deng, Siyu Hou, Xianbo Xia, Wei Zhao, Xingyu Zhu, Yang Zhang, Chao Wang, Ling Xu, Jinlin Song   +9 more
wiley   +1 more source

Alternating High‐Fat and Polysaccharide Diets Modulates Gut Phage‐Bacterial Interplay

Advanced Science, EarlyView.
This study reveals how alternating high‐fat and polysaccharide diets reshape the human gut virome and enhance phage‐bacteria interactions. Using large‐scale metagenomic meta‐analysis and a time‐resolved mouse model, the authors show that diets strongly modulate phage abundance, lifestyle, and gene exchange, offering new insights into nutrition‐guided ...
Fengxiang Zhao, Ruiqi Zhang, Rujun Wei, Huimin Fan, Yongfei Hu, Wenyu Shi, Jinfeng Wang   +6 more
wiley   +1 more source

Bayesian hierarchical models for analysing the spatial distribution of bioclimatic indices [PDF]

, 2017
A methodological approach for modelling the spatial distribution of bioclimatic indices is proposed in this paper. The value of the bioclimatic index is modelled with a hierarchical Bayesian model that incorporates both structured and unstructured random
Barber, Antoni, Barber, Xavier, Conesa Ortega, David, Lopez-Quílez, Antonio, Mayoral, Asuncion, Morales, Javier   +5 more
core  

Maternal Preconception Antibiotic Exposure Disrupts Microbial Succession: A Transgenerational Risk for Offspring Gut Mucosal Immaturity and Colitis Susceptibility

Advanced Science, EarlyView.
This study reveals that maternal antibiotic exposure prior to conception disrupts intergenerational gut microbial succession. By enhancing maternal‐offspring microbial transmission, altering microbial developmental trajectories and increasing selective pressures during community assembly, these disturbances lead to persistent gut mucosal immaturity and
Yuzhu Chen, Ruqiao Duan, Cunzheng Zhang, Gaonan Li, XiaoLin Ji, Qi Zhang, Fei Pei, Kun Wang, Liping Duan   +8 more
wiley   +1 more source

Genome‐Wide Association Study Reveals Insect Genetics and Microbial Symbiont Effects on Susceptibility of Diaphorina citri to the Citrus Greening Pathogen, Candidatus Liberibacter Asiaticus

Advanced Science, EarlyView.
This study investigates the genetic and microbial factors influencing the susceptibility of Diaphorina citri to the citrus greening pathogen Candidatus Liberibacter asiaticus (CLas), employing a microbiome Genome Wide Association Study. The research identifies a key gene encoding an MFS‐type transporter contributing to CLas infectivity and abundance in
Kai Liu, Qingcui He, Zeyue Lin, Shixuan Huang, Zichun Zhong, Pingyang Zhu, Mengge Gao, Luyao Zhao, Han Jin, Guiting Wu, Gurr M. Geoff, Qunxin Han, Rui Pang   +12 more
wiley   +1 more source

Climate Change Assessment in Brazil: Utilizing the Köppen-Geiger (1936) Climate Classification

Revista Brasileira de Meteorologia
Analyses and climate forecasts indicate significant changes in climate elements, particularly the global mean temperature, and variations in rainfall patterns, which can have profound effects on ecosystems and agriculture.
Rafael Fausto de Lima, Lucas Eduardo de Oliveira Aparecido, Guilherme Botega Torsoni, Glauco de Souza Rolim   +3 more
doaj   +1 more source