Results 51 to 60 of about 93,806 (299)

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Biofuel technologies: Lessons learned and pathways to decarbonization

GCB Bioenergy, 2023
This Opinion highlights several successful cases of biofuel technologies recently described by the IEA Bioenergy Intertask Report on Lessons Learned.
Heitor Cantarella, Jean Felipe Leal Silva, Luiz Augusto Horta Nogueira, Rubens Maciel Filho, Raffaella Rossetto, Tomas Ekbom, Glaucia Mendes Souza, Franziska Mueller‐Langer   +7 more
doaj   +1 more source

The Role of Calcitonin Gene‐Related Peptide in High‐Altitude Headache: A Prospective Field Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective High‐altitude headache (HAH) is a common neurological condition associated with rapid ascent to high altitude. The pathophysiological mechanisms underlying HAH remain incompletely understood. Calcitonin gene‐related peptide (CGRP), a neuropeptide implicated in migraine pathophysiology, may play a key role in the pathophysiology of ...
Roman Schniepp, Ludwig Karrasch, Helena Breitenstein, Andreas Straube, Katharina Kamm   +4 more
wiley   +1 more source

Climate Crisis, Political Crisis

, 2022
By completely destroying the city of Paradise (27,000 inhabitants) and its surroundings, the deadliest fire in the history of the United States caused a major shock both for individuals and for socio-political institutions, opening then the possibility for voices kept out of the way to be heard regarding the redefinition of the relationship with the ...
openaire   +1 more source

Comparing the Effect of Semi‐Immersive Virtual Reality, Computerized Cognitive Training, and Traditional Rehabilitation on Cognitive Function in Multiple Sclerosis: A Randomized Clinical Trial

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Cognitive impairment is a common non‐motor symptom in Multiple Sclerosis (MS), negatively affecting autonomy and Quality of Life (QoL). Innovative rehabilitation strategies, such as semi‐immersive virtual reality (VR) and computerized cognitive training (CCT), may offer advantages over traditional cognitive rehabilitation (TCR ...
Maria Grazia Maggio, Desiree Latella, Lilla Bonanno, Paulo Cezar Rocha dos Santos, Marcos Maldonado‐Díaz, Meir Plotnik, Rosaria De Luca, Angelo Quartarone, Rocco Salvatore Calabrò   +8 more
wiley   +1 more source

Impact of climate change on water crisis and conflicts: Farmers’ perceptions at the ZayandehRud Basin in Iran

Journal of Hydrology: Regional Studies
Study region: The study was conducted in the ZayandehRud Basin in Iran. Study focus: Conflicts over water resources have increasingly occurred on different geographic scales, linked to various human activities and environmental factors, including climate
Ladan Naderi, Esmail Karamidehkordi, Mohammad Badsar, Mehrdad Moghadas   +3 more
doaj   +1 more source

REVIEW: Timely climate media strategy to empower citizens

Pacific Journalism Review, 2017
Journalism and Climate Crisis: Public Engagement, Media Alternatives, edited by Robert A. Hackett, Susan Forde, Shane Gunster and Kerrie Foxwell-Norton. Abingdon, UK: Routledge. 2017. 204 pages.
David Robie
doaj   +1 more source

Sertraline Treatment Can Mimic Niemann‐Pick Type C Biomarker Profile: A Diagnostic Pitfall

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Oxysterols (cholestane‐3β,5α,6β‐triol and 7‐ketocholesterol) and N‐palmitoyl‐O‐phosphocholineserine (PPCS) are sensitive biomarkers for Niemann‐Pick disease type C (NPC) screening. However, false‐positive results occur, with a biomarker profile suggestive of NPC despite the absence of pathogenic variants in genes involved in NPC or ...
Maria Makrygianni, Cecile Pagan, Antony Citterio‐Quentin, Isabelle Rouvet, Giulia Dingeo, Cyril Hanin, Claudine Laurent‐Levinson, Samia Pichard, Bénédicte Héron, Clément Gourguechon, Daniele Mandia, Jerome Guitton, Carole Lacout, Nicolas Schleinitz, Florient Potier, Olivier Flabeau, Elsa Besse‐Pinot, Foudil Lamari, Magali Pettazzoni, Yann Nadjar   +19 more
wiley   +1 more source

The Extinction Rebellion and going beyond politics: can deliberation be the answer in climate mitigation?

Fennia: International Journal of Geography
The United Nations (UN) has characterized the climate crisis as ‘the defining crisis of our time’ (United Nations 2023). To address the crisis in the 2020s, the so-called new climate movement has emerged to protest the inadequate climate action taken by ...
Janette Huttunen
doaj   +1 more source

The 3‐Machines Energy Transition Model: Exploring the Energy Frontiers for Restoring a Habitable Climate

Earth's Future, 2022
To stabilize the climate, we need to urgently decarbonize our society and remove excess CO2 from the atmosphere. Ambitions for the transformation are ultimately limited by bio‐physical constraints, which cannot be transgressed even if all economic and ...
Harald Desing, Andreas Gerber, Roland Hischier, Patrick Wäger, Rolf Widmer   +4 more
doaj   +1 more source