Results 81 to 90 of about 3,178,795 (372)
The contested politics of climate change and the crisis of neo-liberalism [PDF]
Climate change must be placed in relation to broader contestation of unequal social and environmental relations and specifically in relation to the crisis of neoliberalism.
Featherstone, D.J.
core
Logistics and climate: an assessment of logistics’ multiple roles in the climate crisis
Efforts to mitigate climate change and manage its consequences are becoming increasingly reliant on logistics. Logistics’ contribution is currently under-estimated by policymakers and researchers.
Alan C. McKinnon
semanticscholar +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Redefining the Quest for Health Equity in the Era of Climate Crisis [PDF]
Alicia R. Riley
openalex +1 more source
Education responses to climate change and quality : two parts of the same agenda? [PDF]
Increasing attention to climate change and the current global economic crisis has underscored the need for approaches to education that equip and empower people of all ages to deal with uncertain environmental, economic and political futures.
Bangay, Colin, Blum, Nicole
core +3 more sources
Indigenous-Led Nature-Based Solutions for the Climate Crisis: Insights from Canada
This article provides an international and national overview of climate change and biodiversity frameworks and is focused on emerging evidence of Indigenous leadership and collaborations in Canada.
Brennan Vogel +3 more
semanticscholar +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Recent years have seen another peak in global media attention to climate change. Driven by increasingly dire news about extreme weather, growing demands of systemic adaption and a new wave political activism, the current situation has increasingly been ...
Kunelius Risto, Roosvall Anna
doaj +1 more source
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source
Managing pandemics as super wicked problems: lessons from, and for, COVID-19 and the climate crisis
COVID-19 has caused 100s of millions of infections and millions of deaths worldwide, overwhelming health and economic capacities in many countries and at multiple scales.
G. Auld +3 more
semanticscholar +1 more source

