Results 41 to 50 of about 107,890 (307)

Accuracy of the mean sea level continuous record with future altimetric missions: Jason-3 vs. Sentinel-3a [PDF]

Ocean Science, 2016
The current mean sea level (MSL) continuous record, essential to understanding the climate evolution, is computed with the altimetric measurements of the TOPEX/Poseidon mission, succeeded by Jason-1 and later Jason-2.
L. Zawadzki, M. Ablain
doaj   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

CLARA-A2: the second edition of the CM SAF cloud and radiation data record from 34 years of global AVHRR data [PDF]

Atmospheric Chemistry and Physics, 2017
The second edition of the satellite-derived climate data record CLARA (The CM SAF Cloud, Albedo And Surface Radiation dataset from AVHRR data – second edition denoted as CLARA-A2) is described.
K.-G. Karlsson, K. Anttila, J. Trentmann, M. Stengel, J. Fokke Meirink, A. Devasthale, T. Hanschmann, S. Kothe, E. Jääskeläinen, J. Sedlar, N. Benas, G.-J. van Zadelhoff, C. Schlundt, D. Stein, S. Finkensieper, N. Håkansson, R. Hollmann   +16 more
doaj   +1 more source

Assessment of the EUMETSAT Multi Decadal Land Surface Albedo Data Record from Meteosat Observations

Remote Sensing, 2021
Surface albedo, defined as the ratio of the surface-reflected irradiance to the incident irradiance, is one of the parameters driving the Earth energy budget and it is for this reason an essential variable in climate studies. Instruments on geostationary
Alessio Lattanzio, Michael Grant, Marie Doutriaux-Boucher, Rob Roebeling, Jörg Schulz   +4 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

FEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero, Maria Kopsida, Nathalie Arendt, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx   +5 more
wiley   +1 more source

A Solar Irradiance Climate Data Record

Bulletin of the American Meteorological Society, 2016
Abstract We present a new climate data record for total solar irradiance and solar spectral irradiance between 1610 and the present day with associated wavelength and time-dependent uncertainties and quarterly updates. The data record, which is part of the National Oceanic and Atmospheric Administration’s (NOAA) Climate Data Record (CDR)
O. Coddington, J. L. Lean, P. Pilewskie, M. Snow, D. Lindholm   +4 more
openaire   +1 more source

The Passive Microwave Neural Network Precipitation Retrieval Algorithm for Climate Applications (PNPR-CLIM): Design and Verification

Remote Sensing, 2021
This paper describes the Passive microwave Neural network Precipitation Retrieval algorithm for climate applications (PNPR-CLIM), developed with funding from the Copernicus Climate Change Service (C3S), implemented by ECMWF on behalf of the European ...
Leonardo Bagaglini, Paolo Sanò, Daniele Casella, Elsa Cattani, Giulia Panegrossi   +4 more
doaj   +1 more source

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source

Climate and environment of a Pliocene warm world [PDF]

, 2011
The Pliocene Epoch, 5.33–2.58 million years ago (Ma), was a generally warmer and wetter interval with atmospheric CO2-concentrations at or slightly above modern levels.
Johnson, Andrew L.A., Kender, Sev, Haywood, Alan, Sev Kender, Johnson, Andrew, Williams, Mark, Haywood, Alan M., Mark Williams, Jan Zalasiewicz, Zalasiewicz, Jan, Ulrich Salzmann, Andrew L.A. Johnson, Salzmann, Ulrich, Alan M. Haywood   +13 more
core   +1 more source