Results 91 to 100 of about 1,748,129 (280)

Predictive use of the Maximum Entropy Production principle for Past and Present Climates

, 2013
In this paper, we show how the MEP hypothesis may be used to build simple climate models without representing explicitly the energy transport by the atmosphere. The purpose is twofold. First, we assess the performance of the MEP hypothesis by comparing a
A Kleidon, A Kleidon, A Lacis, C Herbert, C Herbert, C Rodgers, D Johnson, D. Paillard, G Grinstein, G Holloway, G Paltridge, G Paltridge, G Roe, G Stephens, H Grassl, H Ozawa, J Gerard, J Holton, J Pedlosky, JL Dufresne, JP Peixoto, L Martyushev, MHP Ambaum, N Renno, O Marti, P Wyant, R Dewar, R Dewar, R Goody, R Lorenz, R McClatchey, R Pierrehumbert, S Bruers, S Pascale, T Ito, T Kunz, T Lenton, TE Jupp, TJ Crowley, V. Lucarini   +39 more
core   +2 more sources

An Out‐of‐Place Etiology: Recognizing FMR1 Premutation in the Memory Clinic

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT The FMR1 gene premutation (55–200 CGG repeats) is usually associated with a wide range of symptoms and phenotypes within the Fragile X‐tremor/ataxia syndrome (FXTAS), but may also manifest as predominant or isolated cognitive decline. We describe three male patients referred for progressive cognitive impairment and behavioral changes. Standard
Guido Greco, Caterina Motta, Enrica Marchionni, Maria Rosaria D'Apice, Carlangelo Carrese, Giuseppe Novelli, Alessandro Martorana, Chiara Giuseppina Bonomi   +7 more
wiley   +1 more source

Variably Protease‐Sensitive Prionopathy: Two New Cases With Motor Neuron‐Dementia Syndrome

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT We describe two patients with variably protease‐sensitive prionopathy (VPSPr) who developed progressive upper motor neuron symptoms, insomnia, behavioral and cognitive decline, compatible with primary lateral sclerosis associated with frontotemporal dementia (FTD).
María Elena Erro, María Victoria Zelaya, Hasier Eraña, Javier Sánchez Ruiz de Gordoa, Fermín García‐Amigot, Anika Simonovska‐Serra, María Cristina Caballero, Isidre Ferrer, Ellen Gelpi, Ivonne Jericó, Joaquín Castilla   +10 more
wiley   +1 more source

Neuropsychiatric Symptoms Mimicking Dementia in a Patient Treated With Imatinib

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Tyrosine kinase inhibitors are the cornerstone of chronic myeloid leukemia treatment. Newer agents have more potency and a broader spectrum of action, but also a higher potential for neuropsychiatric side effects. We present a case of a patient on imatinib who developed progressive cognitive, mood, and behavioral alterations.
Ashley Jones, Samuele Bonomi, Keith E. Stockerl‐Goldstein, Randall J. Bateman   +3 more
wiley   +1 more source

Remote Assessment of Ataxia Severity in SCA3 Across Multiple Centers and Time Points

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Spinocerebellar ataxia type 3 (SCA3) is a genetically defined ataxia. The Scale for Assessment and Rating of Ataxia (SARA) is a clinician‐reported outcome that measures ataxia severity at a single time point. In its standard application, SARA fails to capture short‐term fluctuations, limiting its sensitivity in trials.
Marcus Grobe‐Einsler, Vivian Maas, Arian Taheri Amin, Jennifer Faber, Tamara Schaprian, Katharina Hill, Matthis Synofzik, Lisa H. Graf, Heike Jacobi, Manuela Lima, Ana F. Ferreira, Bart P. van de Warrenburg, Ilse H. J. Willemse, Dagmar Timmann, Andreas Thieme, Paola Giunti, Hector Garcia‐Moreno, Magda M. Santana, Jeannette Hübener‐Schmid, Elin H. Davies, Thomas Klockgether   +20 more
wiley   +1 more source

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel, Timothy P. Siejka, Cassandra Marotta, Josh J. Y. Lee, Kelly Bertram, Terence J. O'Brien, Meng Law, Lucy Vivash, Ian H. Harding   +8 more
wiley   +1 more source

A Scoping Review on Artificial Intelligence–Supported Interventions for Nonpharmacologic Management of Chronic Rheumatic Diseases

Arthritis Care &Research, EarlyView.
This review summarizes artificial intelligence (AI)‐supported nonpharmacological interventions for adults with chronic rheumatic diseases, detailing their components, purpose, and current evidence base. We searched Embase, PubMed, Cochrane, and Scopus databases for studies describing AI‐supported interventions for adults with chronic rheumatic diseases.
Nirali Shah, Alexis Castellanos, Yen Chen, John Piette, Amy Bucher, Susan Murphy   +5 more
wiley   +1 more source

Mediterranean climate future: an insightful look into the Basin’s precipitation response to greenhouse gas forcing

Environmental Research Letters, 2015
In a new investigation of model projections of greenhouse gas warming impact on the Mediterranean, Zappa et al (2015 Environ. Res. Lett. http://dx.doi.org/10.1088/1748-9326/10/10/104012 10 http://dx.doi.org/10.1088/1748-9326/10/10/104012 ) find that the ...
Y Kushnir
doaj   +1 more source

Long-term variability, extremes and changes in temperature and hydrometeorology in the Amazon region: A review [PDF]

Acta Amazonica
This review discusses observed hydroclimatic trends and future climate projections for the Amazon. Warming over this region is a fact, but the magnitude of the warming trend varies depending on the datasets and length of the analyzed period.
Jose Antonio MARENGO, Jhan-Carlo ESPINOZA, Rong FU, Juan Carlos JIMENEZ MUÑOZ, Lincoln Muniz ALVES, Humberto Ribeiro DA ROCHA, Jochen SCHÖNGART   +6 more
doaj   +1 more source

Early climate on earth-reduced gas models and early climate on Mars-reduced gas and obliquity models [PDF]

At high obliquity, Martian polar ground temperatures could exceed the melting point of ice for considerable periods of time (approximately 90 Earth days). Under special conditions ice itself might melt.
Sagan, C., Toon, O. B.
core   +1 more source