Results 171 to 180 of about 293,074 (268)

Wind power density in areas of Northeastern Brazil from Regional Climate Models for a recent past. [PDF]

PLoS One
Gurgel ARC, Sales DC, Lima KC.
europepmc   +1 more source

Targeted Restoration of the Microbial Tryptophan Oxidative Pathway Ameliorates Autism‐Like Behavioral and Synaptic Deficits

Advanced Science, EarlyView.
ABSTRACT Autism Spectrum Disorder (ASD) is associated with gut microbiota dysbiosis, yet the contribution of specific microbial metabolic pathways remains unclear. Reanalysis of a public ASD cohort revealed reduced functional potential in microbial tryptophan oxidative metabolism.
Rui Guo, Caian He, Xiao Xiao, Jingmeng Li, Zilong Zhang, Ying He, Chuanchuan Wang, Jiale Zhao, Jun Gong, Jiarui Liang, Tian Yuan, Haiting Sun, Xuebo Liu, Chao Gao, Zhigang Liu   +14 more
wiley   +1 more source

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

Advanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong, Ming Ho Yam, Jiaxin Zhang, Lin Du, Linbin Zhou, Yolanda Wong Ying Yip, Bo Man Ho, Hemlata Bisnauthsing, Jiahui Li, Ivan Kong, Shushu Xu, Changzhen Fu, Karl K.H. So, Joaquim S.L. Vong, Ling‐Ping Cen, Ming‐Ming Yang, Khazeema Yousaf, Mai Har Sham, Sun On Chan, Poemen P. Chan, Chi Pui Pang, Clement C. Tham, Jing Na He, Jian Li, Wai Kit Chu   +24 more
wiley   +1 more source

Observed humidity trends in dry regions contradict climate models. [PDF]

Proc Natl Acad Sci U S A
Simpson IR, McKinnon KA, Kennedy D, Lawrence DM, Lehner F, Seager R.   +5 more
europepmc   +1 more source

Natural Variation in ZmASB1 Links Tryptophan Metabolism to Root Growth and Drought Tolerance in Maize

Advanced Science, EarlyView.
Natural variation in the maize ZmASB1 promoter regulates tryptophan accumulation, root development, and drought tolerance through a tryptophan–auxin pathway. A 5‐bp InDel alters ZmDOF17 binding and promoter activity, and the favorable allele is enriched during breeding. These findings reveal a cis‐regulatory mechanism linking amino acid metabolism with
Xiaoyi Yang, Houmiao Wang, Xiaomin Zhang, Yunyun Wang, Yimei Tian, Baoqing Wang, Tianze Zhu, Shuai Fang, Wei Li, Wenye Rui, Yining Zhang, Dan Sun, Haoxin Gao, Yuxuan Li, Zhongtao Jia, Zefeng Yang, Chenwu Xu, Pengcheng Li   +17 more
wiley   +1 more source

Impact scenarios on groundwater availability of southern Italy by joint application of regional climate models (RCMs) and meteorological time series. [PDF]

Sci Rep
Lepore D, Bucchignani E, Montesarchio M, Allocca V, Coda S, Cusano D, De Vita P.   +6 more
europepmc   +1 more source

A round Earth for climate models. [PDF]

Proc Natl Acad Sci U S A, 2019
Prather MJ, Hsu JC.
europepmc   +1 more source

Weaker Links Between Zonal Convective Clustering and ITCZ Width in Climate Models Than in Observations. [PDF]

Geophys Res Lett, 2020
Popp M, Lutsko NJ, Bony S.
europepmc   +1 more source

Gm26550 Modulates Learning and Memory by Increasing IGF1 mRNA Expression and Stability in Nrf2−/− Mice

Advanced Science, EarlyView.
The present study shows that Nrf2 directly binds to the Gm26550 promoter, thereby activating Gm26550 transcription and increasing its expression. Mechanistically, Gm26550 promotes IGF1 expression by functionally antagonizing miR‐26a‐5p‐mediated repression and sequestering the RBP KHSRP, thereby enhancing hippocampal neuronal synaptic plasticity and ...
Hongfang Wang, Ziyao Wang, Dongyue Zuo, Zhaowen Su, Bowen Song, Jiamin Gao, Yizhou Zhang, Ruiting Zhao, Linjie Sun, Mengdi Li, Yirui Fan, Dandan Geng, Lei Wang   +12 more
wiley   +1 more source

Development of maximum relevant prior feature ensemble (MRPFE) index to characterize future drought using global climate models. [PDF]

Sci Rep
Gul A, Qamar S, Yousaf M, Ali Z, Alshahrani M, Hilali SO.   +5 more
europepmc   +1 more source