Results 201 to 210 of about 2,906,823 (288)

A Tac1‐Expressing Brainstem Pathway Underlies the Pathogenesis of Trigeminal Neuralgia

Advanced Science, EarlyView.
A critical TG‐Sp5CTac1‐PBNTac1 pathway drives trigeminal neuropathic pain (TNP). Tac1‐expressing parabrachial nucleus (PBNTac1) neurons exhibit heightened responses to innocuous stimuli in TNP, and chemogenetic inhibition of these neurons effectively prevents TNP development.
Liting Sun, Jia‐Jia Wang, Xiang‐Yu Li, Xin‐Yi Lin, Juan Li, Qiu‐Tong Yu, Zi‐Han Wang, Xue‐Ping Gao, Lei Jin, Wei‐Ke Li, Tian‐Lin Cheng, Juan Deng   +11 more
wiley   +1 more source

Climate change and Variability

Journal of Agrometeorology, 2013
B.V. RAMANA RAO
doaj  

Nonlinear and lagged effects of climate variability on dengue incidence in an urban megacity: a distributed lag non-linear model (DLNM) based study in Bangkok, Thailand. [PDF]

BMC Public Health
Polrob W, La-Up A.
europepmc   +1 more source

Decadal Climate Variability and Predictability: Challenges and Opportunities

, 2017
C. Cassou, Y. Kushnir, E. Hawkins, A. Pirani, F. Kucharski, I. Kang, N. Caltabiano   +6 more
semanticscholar   +1 more source

OTUD6A in Airway Epithelial Cells Exacerbates Allergic Asthma by Promoting Airway Inflammation and Airway Remodeling Through Deubiquitination of hResistin/mRELMα

Advanced Science, EarlyView.
This study elucidates a novel mechanistic role of the deubiquitinase OTUD6A in asthma pathogenesis, uncovering its regulatory function in airway inflammation and airway remodeling through the stabilization of hResistin/mRELMα. This study offers a novel regulatory axis (OTUD6A‐hResistin/mRELMα) in asthma pathogenesis and OTUD6A inhibition as a potential
Weiting Pan, Xinru Xi, Wei Dai, Tingfang Xiao, Yeqing Chen, Xuanyu Chen, Xiangting Ge, Chengguang Zhao, Hui Zhang, Yali Zhang, Weixi Zhang   +10 more
wiley   +1 more source

Climate variability links to changes in Rioja wine (Spain). [PDF]

Int J Biometeorol
Rasilla DF, Aransay R, Conde-Oria F.
europepmc   +1 more source

TOGR3, a Proteasome β4 Subunit, Orchestrates Sugar Homeostasis to Trade Off Growth and Thermotolerance in Rice

Advanced Science, EarlyView.
This study identifies a novel thermoregulatory mechanism in rice: TOGR3 partners with 26S proteasome subunits, including TT1, to drive thermoresponsive ubiquitin–proteasome activity, maintaining sugar homeostasis in stomatal regulation to balance growth and stress resistance.
Biyao Zhang, Xiaoyan Wu, Ting Xu, Feifei Guo, Xiaolu Shen, Cuiping Meng, Yanan Wang, Xue Han, Hong Zhao, Yongbiao Xue   +9 more
wiley   +1 more source

Orbital (Hydro)Climate Variability in the Ice-Free Early Eocene Arctic. [PDF]

Paleoceanogr Paleoclimatol
Fokkema CD, Brinkhuis H, Peterse F, Sluijs A.   +3 more
europepmc   +1 more source

Alternating High‐Fat and Polysaccharide Diets Modulates Gut Phage‐Bacterial Interplay

Advanced Science, EarlyView.
This study reveals how alternating high‐fat and polysaccharide diets reshape the human gut virome and enhance phage‐bacteria interactions. Using large‐scale metagenomic meta‐analysis and a time‐resolved mouse model, the authors show that diets strongly modulate phage abundance, lifestyle, and gene exchange, offering new insights into nutrition‐guided ...
Fengxiang Zhao, Ruiqi Zhang, Rujun Wei, Huimin Fan, Yongfei Hu, Wenyu Shi, Jinfeng Wang   +6 more
wiley   +1 more source

Insights into climate variability of the meteorological records from a background monitoring station: the Giordan lighthouse, Gozo. [PDF]

Open Res Eur
Ciarlo J, Vella R, Saliba M, Ellul R, Micallef A, Coppola E, Micallef A, Mifsud D.   +7 more
europepmc   +1 more source