Results 201 to 210 of about 162,320 (260)

A Skull Bone Marrow‐to‐Brain Axis Links Osteoblastic Activity to Myeloid Cell Trafficking, Cerebral Blood Flow, and Cognition in Alzheimer's Progression

open access: yesAdvanced Science, EarlyView.
This study reveals that Alzheimer's disease–linked APP expression in bone‐forming cells drives skull bone marrow remodeling and alters its vascular connections to the brain. These changes disrupt immune cell trafficking, cerebral blood flow, and cognition. Targeting bone marrow macrophages restores brain function, highlighting a previously unrecognized
Lei Xiong   +6 more
wiley   +1 more source

Asynchronicity of deglacial permafrost thawing controlled by millennial-scale climate variability. [PDF]

open access: yesNat Commun
Yan X   +12 more
europepmc   +1 more source

The impact of natural climate variability on the global distribution of Aedes aegypti: a mathematical modelling study. [PDF]

open access: yesLancet Planet Health
Kaye AR   +6 more
europepmc   +1 more source

Climate and climate variability

2010
In the following we describe some basic concepts that are fundamental for understanding (marine) climate and climate variability. We begin with a brief historical review on earlier and more modern concepts of climate and subsequently define marine weather and marine climate as used throughout the remainder of this book (Section 1.2).
Ralf Weisse, Hans von Storch
openaire   +1 more source

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